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@ARTICLE{Werner:22817,
      author       = {Werner, C. F. and Gröbel, S. and Krumbe, C. and Wagner, T.
                      and Selmer, T. and Yoshinobu, T. and Baumann, M. E. M. and
                      Keusgen, M. and Schöning, M. J.},
      title        = {{N}utrient concentration-sensitive microorganism-based
                      biosensor},
      journal      = {Physica status solidi / A},
      volume       = {209},
      number       = {5},
      issn         = {0031-8965},
      address      = {Weinheim},
      publisher    = {Wiley-VCH},
      reportid     = {PreJuSER-22817},
      pages        = {900 - 904},
      year         = {2012},
      note         = {The authors thank the German Federal Ministry of Food,
                      Agriculture and Consumer Protection (BMELV) and the
                      'Fachagentur Nachwachsende Rohstoffe e. V.' (FNR) for
                      financial support of this work (Bio-LAPS).},
      abstract     = {This work presents a biosensor based on living cells
                      immobilised on a light-addressable potentiometric sensor
                      (LAPS). The set-up is sensitive to the concentrations of
                      nutrients metabolised by bacteria, which results in an
                      extracellular acidification. This is exemplarily
                      demonstrated with glucose as nutrient and Escherichia coli
                      as microorganism. The function of this biosensor is
                      comparable to an enzyme-based field-effect sensor when using
                      diffusion limitation. With the help of addressability of the
                      LAPS an on-chip differential set-up was developed. Thus,
                      external influences such as sensor drift, temperature and
                      external pH changes can be minimised. (c) 2012 WILEY-VCH
                      Verlag GmbH $\&$ Co. KGaA, Weinheim},
      keywords     = {J (WoSType)},
      cin          = {PGI-8 / JARA-FIT},
      ddc          = {530},
      cid          = {I:(DE-Juel1)PGI-8-20110106 / $I:(DE-82)080009_20140620$},
      pnm          = {Grundlagen für zukünftige Informationstechnologien},
      pid          = {G:(DE-Juel1)FUEK412},
      shelfmark    = {Materials Science, Multidisciplinary / Physics, Applied /
                      Physics, Condensed Matter},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000303386900017},
      doi          = {10.1002/pssa.201100801},
      url          = {https://juser.fz-juelich.de/record/22817},
}