001     22817
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024 7 _ |2 DOI
|a 10.1002/pssa.201100801
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082 _ _ |a 530
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|a Materials Science, Multidisciplinary
084 _ _ |2 WoS
|a Physics, Applied
084 _ _ |2 WoS
|a Physics, Condensed Matter
100 1 _ |a Werner, C. F.
|b 0
|u FZJ
|0 P:(DE-Juel1)128743
245 _ _ |a Nutrient concentration-sensitive microorganism-based biosensor
260 _ _ |a Weinheim
|b Wiley-VCH
|c 2012
300 _ _ |a 900 - 904
336 7 _ |a Journal Article
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440 _ 0 |a Physica Status Solidi A
|x 0031-8965
|0 4913
|y 5
|v 209
500 _ _ |3 POF3_Assignment on 2016-02-29
500 _ _ |a The authors thank the German Federal Ministry of Food, Agriculture and Consumer Protection (BMELV) and the 'Fachagentur Nachwachsende Rohstoffe e. V.' (FNR) for financial support of this work (Bio-LAPS).
520 _ _ |a This work presents a biosensor based on living cells immobilised on a light-addressable potentiometric sensor (LAPS). The set-up is sensitive to the concentrations of nutrients metabolised by bacteria, which results in an extracellular acidification. This is exemplarily demonstrated with glucose as nutrient and Escherichia coli as microorganism. The function of this biosensor is comparable to an enzyme-based field-effect sensor when using diffusion limitation. With the help of addressability of the LAPS an on-chip differential set-up was developed. Thus, external influences such as sensor drift, temperature and external pH changes can be minimised. (c) 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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|a biosensor
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|a extracellular acidification
653 2 0 |2 Author
|a glucose
653 2 0 |2 Author
|a light-addressable potentiometric sensor
700 1 _ |a Gröbel, S.
|b 1
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700 1 _ |a Krumbe, C.
|b 2
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700 1 _ |a Wagner, T.
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700 1 _ |a Selmer, T.
|b 4
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700 1 _ |a Yoshinobu, T.
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700 1 _ |a Baumann, M. E. M.
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700 1 _ |a Keusgen, M.
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700 1 _ |a Schöning, M. J.
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773 _ _ |a 10.1002/pssa.201100801
|g Vol. 209, p. 900 - 904
|p 900 - 904
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|0 PERI:(DE-600)1481091-8
|t Physica status solidi / A
|v 209
|y 2012
|x 0031-8965
|n 5
856 7 _ |u http://dx.doi.org/10.1002/pssa.201100801
909 C O |o oai:juser.fz-juelich.de:22817
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914 1 _ |y 2012
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