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@ARTICLE{Chen:22913,
author = {Chen, Q. and Weidner, R. and Weiss, P.H. and Marshall, J.C.
and Fink, G.R.},
title = {{N}eural interaction between spatial domain and spatial
reference frame in parietal-occipital junction},
journal = {Journal of cognitive neuroscience},
volume = {24},
issn = {0898-929X},
address = {Cambridge, Mass.},
publisher = {MIT Pr. Journals},
reportid = {PreJuSER-22913},
pages = {2223 - 2236},
year = {2012},
note = {Record converted from VDB: 12.11.2012},
abstract = {On the basis of double dissociations in clinical symptoms
of patients with unilateral visuospatial neglect,
neuropsychological research distinguishes between different
spatial domains (near vs. far) and different spatial
reference frames (egocentric vs. allocentric). In this fMRI
study, we investigated the neural interaction between
spatial domains and spatial reference frames by constructing
a virtual three-dimensional world and asking participants to
perform either allocentric or egocentric judgments on an
object located in either near or far space. Our results
suggest that the parietal-occipital junction (POJ) not only
shows a preference for near-space processing but is also
involved in the neural interaction between spatial domains
and spatial reference frames. Two dissociable streams of
visual processing exist in the human brain: a ventral
perception-related stream and a dorsal action-related
stream. Consistent with the perception-action model, both
far-space processing and allocentric judgments draw upon the
ventral stream whereas both near-space processing and
egocentric judgments draw upon the dorsal stream. POJ showed
higher neural activity during allocentric judgments
(ventral) in near space (dorsal) and egocentric judgments
(dorsal) in far space (ventral) as compared with egocentric
judgments (dorsal) in near space (dorsal) and allocentric
judgments (ventral) in far space (ventral). Because
representations in the dorsal and ventral streams need to
interact during allocentric judgments (ventral) in near
space (dorsal) and egocentric judgments (dorsal) in far
space (ventral), our results imply that POJ is involved in
the neural interaction between the two streams. Further
evidence for the suggested role of POJ as a neural interface
between the dorsal and ventral streams is provided by
functional connectivity analysis.},
cin = {INM-3},
ddc = {400},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89572 - (Dys-)function and Plasticity (POF2-89572)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:22721375},
UT = {WOS:000309604200008},
doi = {10.1162/jocn_a_00260},
url = {https://juser.fz-juelich.de/record/22913},
}