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| Hauptseite > Publikationsdatenbank > Improved remote sensing of surface soil moisture > print |
| 001 | 22932 | ||
| 005 | 20180210142334.0 | ||
| 024 | 7 | _ | |2 pmid |a pmid:17645476 |
| 024 | 7 | _ | |2 DOI |a 10.1117/2.1201209.004470 |
| 037 | _ | _ | |a PreJuSER-22932 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 620 |
| 100 | 1 | _ | |a Montzka, C. |b 0 |u FZJ |0 P:(DE-Juel1)VDB51558 |
| 245 | _ | _ | |a Improved remote sensing of surface soil moisture |
| 260 | _ | _ | |c 2012 |a Bellingham, Wash. |
| 300 | _ | _ | |a . |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |a SPIE Newsroom |x 1818-2259 |0 15562 |y . |v . |
| 500 | _ | _ | |3 POF3_Assignment on 2016-02-29 |
| 500 | _ | _ | |a Record converted from VDB: 12.11.2012 |
| 520 | _ | _ | |a As liver fibrosis is the result of persistent necroinflammation in the liver, pro-inflammatory cytokines secreted in response to cell injury have a central role in the pathogenesis of liver fibrosis. We aimed to investigate the association of cytokine gene polymorphism and liver fibrosis among Chinese patients with chronic hepatitis B.Polymorphisms at interleukin-10 (IL-10-627, -1117), interleukin-1-beta (IL-1beta-511, -31, -3964), interleukin-1 receptor antagonist (IL-1RN), and tumor necrosis factor-alpha (TNF-alpha-308, -238) among Chinese chronic hepatitis B patients were determined. Severe liver fibrosis was defined as Ishak fibrosis score = 4 (of 6).Fifty-nine of 273 (22%) patients had severe fibrosis. The distribution of genotypes for IL-10-627 was CC (11%), CA (41%), and AA (48%). The CC genotype at IL-10-627 was protective against severe fibrosis (odds ratio (OR) 0.11; 95% CI 0.014-0.82; P = 0.032). After adjusted for baseline variables, the adjusted OR of CC genotypes at IL-10-627 for severe fibrosis was 0.063 (95% CI 0.06-0.64; P = 0.063). Other gene polymorphisms at IL-1beta, IL-1RN, TNF-alpha, and IL-10 had no significant association with severe fibrosis. Weak linkage disequilibrium was observed between IL-10-627 and IL-10-1117 with linkage disequilibrium coefficient of 0.12 (P < 0.001). The distribution of haplotypes of IL-10-1117 and IL-10-627 was A-A (69%), A-C (26%), and G-C (5%). High and intermediate IL-10 production (A-C and G-C) haplotypes were protective against severe fibrosis (OR 0.62; 95% CI 0.39-0.99; P = 0.046).High production genotype and haplotypes of IL-10 were associated with less severe liver fibrosis in chronic hepatitis B in Chinese. |
| 536 | _ | _ | |a Terrestrische Umwelt |c P24 |2 G:(DE-HGF) |0 G:(DE-Juel1)FUEK407 |x 0 |
| 588 | _ | _ | |a Dataset connected to Pubmed |
| 650 | _ | 2 | |2 MeSH |a Adult |
| 650 | _ | 2 | |2 MeSH |a Female |
| 650 | _ | 2 | |2 MeSH |a Hepatitis B, Chronic: complications |
| 650 | _ | 2 | |2 MeSH |a Humans |
| 650 | _ | 2 | |2 MeSH |a Interleukin 1 Receptor Antagonist Protein: genetics |
| 650 | _ | 2 | |2 MeSH |a Interleukin-10: genetics |
| 650 | _ | 2 | |2 MeSH |a Interleukin-1beta: genetics |
| 650 | _ | 2 | |2 MeSH |a Liver Cirrhosis: complications |
| 650 | _ | 2 | |2 MeSH |a Liver Cirrhosis: genetics |
| 650 | _ | 2 | |2 MeSH |a Male |
| 650 | _ | 2 | |2 MeSH |a Polymorphism, Genetic |
| 650 | _ | 2 | |2 MeSH |a Tumor Necrosis Factor-alpha: genetics |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a IL1RN protein, human |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Interleukin 1 Receptor Antagonist Protein |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Interleukin-1beta |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Tumor Necrosis Factor-alpha |
| 650 | _ | 7 | |0 130068-27-8 |2 NLM Chemicals |a Interleukin-10 |
| 700 | 1 | _ | |a Vereecken, H. |b 1 |u FZJ |0 P:(DE-Juel1)129549 |
| 773 | _ | _ | |0 PERI:(DE-600)2619543-4 |a 10.1117/2.1201209.004470 |t SPIE newsroom |x 1818-2259 |y 2012 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1117/2.1201209.004470 |
| 909 | C | O | |o oai:juser.fz-juelich.de:22932 |p VDB |
| 913 | 1 | _ | |b Erde und Umwelt |k P24 |l Terrestrische Umwelt |1 G:(DE-HGF)POF2-240 |0 G:(DE-Juel1)FUEK407 |2 G:(DE-HGF)POF2-200 |v Terrestrische Umwelt |x 0 |
| 913 | 2 | _ | |a DE-HGF |b Marine, Küsten- und Polare Systeme |l Terrestrische Umwelt |1 G:(DE-HGF)POF3-250 |0 G:(DE-HGF)POF3-259H |2 G:(DE-HGF)POF3-200 |v Addenda |x 0 |
| 914 | 1 | _ | |y 2012 |
| 915 | _ | _ | |a Peer Review unknown |0 StatID:(DE-HGF)0040 |2 StatID\ |
| 920 | 1 | _ | |k IBG-3 |l Agrosphäre |g IBG |0 I:(DE-Juel1)IBG-3-20101118 |x 0 |
| 970 | _ | _ | |a VDB:(DE-Juel1)139756 |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a ConvertedRecord |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a I:(DE-Juel1)IBG-3-20101118 |
| 980 | _ | _ | |a UNRESTRICTED |
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