000022961 001__ 22961
000022961 005__ 20200423203258.0
000022961 0247_ $$2DOI$$a10.1128/AEM.69.3.1759-1774.2003
000022961 0247_ $$2WOS$$aWOS:000181435600055
000022961 0247_ $$2Handle$$a2128/2406
000022961 037__ $$aPreJuSER-22961
000022961 041__ $$aeng
000022961 082__ $$a570
000022961 084__ $$2WoS$$aBiotechnology & Applied Microbiology
000022961 084__ $$2WoS$$aMicrobiology
000022961 1001_ $$0P:(DE-Juel1)128982$$aPolen, T.$$b0$$uFZJ
000022961 245__ $$aDNA microarray analyses of the long-term adaptive response of Escherichia coli to acetate and propionate
000022961 260__ $$aWashington, DC [u.a.]$$bSoc.$$c2003
000022961 300__ $$a1759 - 1774
000022961 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000022961 3367_ $$2DataCite$$aOutput Types/Journal article
000022961 3367_ $$00$$2EndNote$$aJournal Article
000022961 3367_ $$2BibTeX$$aARTICLE
000022961 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000022961 3367_ $$2DRIVER$$aarticle
000022961 440_0 $$08561$$aApplied and Environmental Microbiology$$v69$$x0099-2240$$y3
000022961 500__ $$aRecord converted from VDB: 12.11.2012
000022961 520__ $$aIn its natural environment, Escherichia coli is exposed to short-chain fatty acids, such as acetic acid or propionic acid, which can be utilized as carbon sources but which inhibit growth at higher concentrations. DNA microarray experiments revealed expression changes during exponential growth on complex medium due to the presence of sodium acetate or sodium propionate at a neutral external pH. The adaptive responses to acetate and propionate were similar and involved genes in three categories. First, the RNA levels for chemotaxis and flagellum genes increased. Accordingly, the expression of chromosomal fliC'-'lacZ and flhDC'-'lacZ fusions and swimming motility increased after adaptation to acetate or propionate. Second, the expression of many genes that are involved in the uptake and utilization of carbon sources decreased, indicating some kind of catabolite repression by acetate and propionate. Third, the expression of some genes of the general stress response increased, but the increases were more pronounced after short-term exposure for this response than for the adaptive response. Adaptation to propionate but not to acetate involved increased expression of threonine and isoleucine biosynthetic genes. The gene expression changes after adaptation to acetate or propionate were not caused solely by uncoupling or osmotic effects but represented specific characteristics of the long-term response of E. coli to either compound.
000022961 536__ $$0G:(DE-Juel1)FUEK256$$2G:(DE-HGF)$$aBiotechnologie$$cL02$$x0
000022961 588__ $$aDataset connected to Web of Science
000022961 650_7 $$2WoSType$$aJ
000022961 7001_ $$0P:(DE-Juel1)VDB2832$$aRittmann, D.$$b1$$uFZJ
000022961 7001_ $$0P:(DE-Juel1)VDB1764$$aWendisch, V. F.$$b2$$uFZJ
000022961 7001_ $$0P:(DE-Juel1)128985$$aSahm, H.$$b3$$uFZJ
000022961 773__ $$0PERI:(DE-600)1478346-0$$a10.1128/AEM.69.3.1759-1774.2003$$gVol. 69, p. 1759 - 1774$$p1759 - 1774$$q69<1759 - 1774$$tApplied and environmental microbiology$$v69$$x0099-2240$$y2003
000022961 8567_ $$uhttp://hdl.handle.net/2128/2406$$uhttp://dx.doi.org/10.1128/AEM.69.3.1759-1774.2003
000022961 8564_ $$uhttps://juser.fz-juelich.de/record/22961/files/13980.pdf$$yOpenAccess
000022961 8564_ $$uhttps://juser.fz-juelich.de/record/22961/files/13980.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess
000022961 8564_ $$uhttps://juser.fz-juelich.de/record/22961/files/13980.jpg?subformat=icon-180$$xicon-180$$yOpenAccess
000022961 8564_ $$uhttps://juser.fz-juelich.de/record/22961/files/13980.jpg?subformat=icon-640$$xicon-640$$yOpenAccess
000022961 909CO $$ooai:juser.fz-juelich.de:22961$$pdnbdelivery$$pVDB$$pdriver$$popen_access$$popenaire
000022961 9131_ $$0G:(DE-Juel1)FUEK256$$bLeben$$kL02$$lBiotechnologie$$vBiotechnologie$$x0
000022961 9141_ $$y2003
000022961 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000022961 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000022961 9201_ $$0I:(DE-Juel1)VDB55$$gIBT$$kIBT-1$$lBiotechnologie 1$$x0$$zab 31.10.10 weitergeführt als IBG-1
000022961 970__ $$aVDB:(DE-Juel1)13980
000022961 980__ $$aVDB
000022961 980__ $$aJUWEL
000022961 980__ $$aConvertedRecord
000022961 980__ $$ajournal
000022961 980__ $$aI:(DE-Juel1)IBG-1-20101118
000022961 980__ $$aUNRESTRICTED
000022961 980__ $$aFullTexts
000022961 9801_ $$aFullTexts
000022961 981__ $$aI:(DE-Juel1)IBG-1-20101118