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@ARTICLE{Prechtel:25196,
author = {Prechtel, K. and Bausch, A. R. and Marchi-Artzner, V. and
Kantlehner, M. and Kessler, H. and Merkel, R.},
title = {{D}ynamic force spectroscopy to probe adhesion strength of
living cells},
journal = {Physical review letters},
volume = {89},
issn = {0031-9007},
address = {College Park, Md.},
publisher = {APS},
reportid = {PreJuSER-25196},
pages = {028101-1 - 028101-4},
year = {2002},
note = {Record converted from VDB: 12.11.2012},
abstract = {We studied the mechanical strength of the adhesion of
living cells to model membranes. The latter contained a RGD
lipopeptide which is a high affinity binding site for a cell
adhesion molecule (integrin alpha(V)beta(3)). Cells adhered
specifically to the vesicles. We used micropipette
aspiration for breaking this adhesion with well defined
forces. Systematic variation of the rate of force
application revealed pronounced kinetic effects. The
dependence of the detachment forces on the loading rate was
well described by a power law (exponent approximate to0.4),
in agreement with recent theoretical work.},
keywords = {J (WoSType)},
cin = {ISG-4},
ddc = {550},
cid = {I:(DE-Juel1)VDB44},
pnm = {Kondensierte Materie},
pid = {G:(DE-Juel1)FUEK242},
shelfmark = {Physics, Multidisciplinary},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000176420900033},
doi = {10.1103/PhysRevLett.89.028101},
url = {https://juser.fz-juelich.de/record/25196},
}