000256131 001__ 256131 000256131 005__ 20210129220624.0 000256131 0247_ $$2doi$$a10.1007/978-1-4939-2975-7_4 000256131 037__ $$aFZJ-2015-06140 000256131 041__ $$aEnglish 000256131 1001_ $$0P:(DE-HGF)0$$aKrieger, Patrik$$b0$$eEditor 000256131 245__ $$aSynaptic Microcircuits in the Barrel Cortex 000256131 260__ $$aNew York, NY$$bSpringer New York$$c2015 000256131 29510 $$aSensorimotor Integration in the Whisker System 000256131 300__ $$a59-108 000256131 3367_ $$0PUB:(DE-HGF)7$$2PUB:(DE-HGF)$$aContribution to a book$$bcontb$$mcontb$$s1444740418_31780 000256131 3367_ $$2DRIVER$$abookPart 000256131 3367_ $$2ORCID$$aBOOK_CHAPTER 000256131 3367_ $$07$$2EndNote$$aBook Section 000256131 3367_ $$2BibTeX$$aINBOOK 000256131 3367_ $$2DataCite$$aOutput Types/Book chapter 000256131 520__ $$aAn elementary feature of sensory cortices is thought to be their organisation into functional signal-processing units called ‘cortical columns’. These elementary units process sensory information arriving from peripheral receptors; they are vertically oriented throughout all cortical layers and contain several thousands of excitatory and inhibitory synaptic connections. To understand how sensory signals are transformed into electrical activity in the neocortex it is necessary to elucidate the spatial-temporal dynamics of cortical signal processing and the underlying neurons and synaptic ‘microcircuits’.In the somatosensory barrel cortex there appears to be a structural correlate for the ‘functional’ cortical column. Therefore, it has become an attractive model system to study the synaptic microcircuitry in athe neocortex. Although many synaptic connections in whisker-related cortical ‘columns’ have been characterised over the past years our knowledge is far from complete, in particular with respect to inhibitory connections. In this chapter we will summarise recent data on different excitatory and inhibitory synaptic connections in a whisker-related ‘column’ of the somatosensory cortex and try to outline their function in the neuronal network. This requires an appreciation of the diverse types of excitatory and inhibitory neurons and their function within cortical columns and beyond. When necessary, we will also discuss the synaptic input from and to subcortical structures, in particular the thalamus. However, we will not provide a detailed description of the functional mechanisms of these connections; this is beyond the scope of this chapter. 000256131 536__ $$0G:(DE-HGF)POF3-571$$a571 - Connectivity and Activity (POF3-571)$$cPOF3-571$$fPOF III$$x0 000256131 588__ $$aDataset connected to CrossRef Book 000256131 7001_ $$0P:(DE-HGF)0$$aGroh, Alexander$$b1$$eEditor 000256131 7001_ $$0P:(DE-Juel1)131703$$aRadnikow, Gabriele$$b2$$eCorresponding author$$ufzj 000256131 7001_ $$0P:(DE-Juel1)131702$$aQi, Guanxiao$$b3$$ufzj 000256131 7001_ $$0P:(DE-Juel1)131680$$aFeldmeyer, Dirk$$b4$$ufzj 000256131 773__ $$a10.1007/978-1-4939-2975-7_4 000256131 909CO $$ooai:juser.fz-juelich.de:256131$$pVDB 000256131 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131703$$aForschungszentrum Jülich GmbH$$b2$$kFZJ 000256131 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131702$$aForschungszentrum Jülich GmbH$$b3$$kFZJ 000256131 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131680$$aForschungszentrum Jülich GmbH$$b4$$kFZJ 000256131 9131_ $$0G:(DE-HGF)POF3-571$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$vConnectivity and Activity$$x0 000256131 9141_ $$y2015 000256131 9201_ $$0I:(DE-Juel1)INM-2-20090406$$kINM-2$$lMolekulare Organisation des Gehirns$$x0 000256131 980__ $$acontb 000256131 980__ $$aVDB 000256131 980__ $$aI:(DE-Juel1)INM-2-20090406 000256131 980__ $$aUNRESTRICTED