001     256131
005     20210129220624.0
024 7 _ |a 10.1007/978-1-4939-2975-7_4
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037 _ _ |a FZJ-2015-06140
041 _ _ |a English
100 1 _ |a Krieger, Patrik
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245 _ _ |a Synaptic Microcircuits in the Barrel Cortex
260 _ _ |a New York, NY
|c 2015
|b Springer New York
295 1 0 |a Sensorimotor Integration in the Whisker System
300 _ _ |a 59-108
336 7 _ |a Contribution to a book
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336 7 _ |a bookPart
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336 7 _ |a BOOK_CHAPTER
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520 _ _ |a An elementary feature of sensory cortices is thought to be their organisation into functional signal-processing units called ‘cortical columns’. These elementary units process sensory information arriving from peripheral receptors; they are vertically oriented throughout all cortical layers and contain several thousands of excitatory and inhibitory synaptic connections. To understand how sensory signals are transformed into electrical activity in the neocortex it is necessary to elucidate the spatial-temporal dynamics of cortical signal processing and the underlying neurons and synaptic ‘microcircuits’.In the somatosensory barrel cortex there appears to be a structural correlate for the ‘functional’ cortical column. Therefore, it has become an attractive model system to study the synaptic microcircuitry in athe neocortex. Although many synaptic connections in whisker-related cortical ‘columns’ have been characterised over the past years our knowledge is far from complete, in particular with respect to inhibitory connections. In this chapter we will summarise recent data on different excitatory and inhibitory synaptic connections in a whisker-related ‘column’ of the somatosensory cortex and try to outline their function in the neuronal network. This requires an appreciation of the diverse types of excitatory and inhibitory neurons and their function within cortical columns and beyond. When necessary, we will also discuss the synaptic input from and to subcortical structures, in particular the thalamus. However, we will not provide a detailed description of the functional mechanisms of these connections; this is beyond the scope of this chapter.
536 _ _ |a 571 - Connectivity and Activity (POF3-571)
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588 _ _ |a Dataset connected to CrossRef Book
700 1 _ |a Groh, Alexander
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700 1 _ |a Radnikow, Gabriele
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700 1 _ |a Qi, Guanxiao
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700 1 _ |a Feldmeyer, Dirk
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773 _ _ |a 10.1007/978-1-4939-2975-7_4
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910 1 _ |a Forschungszentrum Jülich GmbH
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913 1 _ |a DE-HGF
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914 1 _ |y 2015
920 1 _ |0 I:(DE-Juel1)INM-2-20090406
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980 _ _ |a UNRESTRICTED


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