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@ARTICLE{Deptua:256564,
author = {Deptuła, Tobiasz and Buitenhuis, Johan and Jarzębski,
Maciej and Patkowski, Adam and Gapinski, Jacek},
title = {{S}ize of submicrometer particles measured by {FCS}:
{C}orrection of the confocal volume},
journal = {Langmuir},
volume = {31},
number = {24},
issn = {1520-5827},
address = {Washington, DC},
publisher = {ACS Publ.},
reportid = {FZJ-2015-06448},
pages = {6681 - 6687},
year = {2015},
abstract = {When fluorescence correlation spectroscopy (FCS) in
combination with a confocal microscope is used to determine
the hydrodynamic radius a of particles comparable to or
larger than the linear size σ of the confocal volume of the
microscope, a correction must be used that depends on the
a2/σ2 ratio and the distribution of the dye within the
particle. Here we present the experimental validation of the
theoretically predicted approximate correction necessary for
appropriate measurements of the size of uniformly
fluorescently labeled spheres of radius comparable to the
size of the confocal volume. We also test the approximate
correction formula for different ranges of the a/σ ratio
and propose a simple procedure to obtain the correct
nanoparticle size from such a measurement.},
cin = {ICS-3},
ddc = {670},
cid = {I:(DE-Juel1)ICS-3-20110106},
pnm = {551 - Functional Macromolecules and Complexes (POF3-551)},
pid = {G:(DE-HGF)POF3-551},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000356992000010},
doi = {10.1021/acs.langmuir.5b01225},
url = {https://juser.fz-juelich.de/record/256564},
}