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@INPROCEEDINGS{Ostermann:278943,
author = {Ostermann, Andreas and Schrader, Tobias Erich and
Monkenbusch, Michael and Laatsch, Bernhard and Jüttner,
Philipp and Petry, Winfried and Richter, Dieter},
title = {{N}eutron macromolecular crystallography at the {FRM}
{IIT}he neutron single crystal diffractometer {BIODIFF}},
reportid = {FZJ-2015-07118},
year = {2015},
abstract = {The research reactor Heinz Maier-Leibnitz (FRM II) is a
modern high flux neutron source which feeds at the present
27 state of the art instruments. The newly build neutron
single crystal diffractometer BIODIFF is especially designed
to collect data from crystals with large unit cells. The
main field of application is the structure analysis of
proteins, especially the determination of hydrogen atom
positions. BIODIFF is a joint project of the
Forschungszentrum Jülich (FZJ/JCNS) and the
Forschungs-Neutronenquelle Heinz Maier-Leibnitz (FRM II).
Typical scientific questions addressed are the determination
of protonation states of amino acid side chains and the
characterization of the hydrogen bonding network between the
protein and an inhibitor or substrate. BIODIFF is designed
as a monochromatic instrument. By using a highly orientated
pyrolytic graphite monochromator (PG002) the diffractometer
is able to operate in the wavelength range of 2.4 Å to
about 5.6 Å. Contaminations of higher order wavelengths are
removed by a neutron velocity selector. To cover a large
solid angle and thus to minimize the data collection time
the main detector of BIODIFF consists of a neutron imaging
plate system in a cylindrical geometry. A Li/ZnS
scintillator CCD camera is available for additional
detection abilities. The main advantage of BIODIFF is the
possibility to adapt the wavelength to the size of the unit
cell of the sample crystal while operating with a clean
monochromatic beam that keeps the background level low.
BIODFF is equipped with a standard Oxford Cryosystem
“Cryostream 700+” which allows measurements in the
temperature regime from 90K up to 500K.},
month = {Aug},
date = {2015-08-24},
organization = {European Crystallographic Meeting,
Rovinj (Croatia), 24 Aug 2015 - 24 Aug
2015},
cin = {JCNS (München) ; Jülich Centre for Neutron Science JCNS
(München) ; JCNS-FRM-II / Neutronenstreuung ; JCNS-1 /
ZEA-1},
cid = {I:(DE-Juel1)JCNS-FRM-II-20110218 /
I:(DE-Juel1)JCNS-1-20110106 / I:(DE-Juel1)ZEA-1-20090406},
pnm = {6G15 - FRM II / MLZ (POF3-6G15) / 6G4 - Jülich Centre for
Neutron Research (JCNS) (POF3-623)},
pid = {G:(DE-HGF)POF3-6G15 / G:(DE-HGF)POF3-6G4},
experiment = {EXP:(DE-MLZ)BIODIFF-20140101},
typ = {PUB:(DE-HGF)24},
url = {https://juser.fz-juelich.de/record/278943},
}