000280487 001__ 280487
000280487 005__ 20240619083522.0
000280487 0247_ $$2doi$$a10.1016/j.bpj.2016.06.003
000280487 0247_ $$2ISSN$$a0006-3495
000280487 0247_ $$2ISSN$$a1542-0086
000280487 0247_ $$2WOS$$aWOS:000380371400024
000280487 037__ $$aFZJ-2016-00257
000280487 041__ $$aEnglish
000280487 082__ $$a570
000280487 1001_ $$0P:(DE-HGF)0$$aGiani, M.$$b0
000280487 245__ $$aClathrin assembly regulated by adaptor proteins in coarse-grained models
000280487 260__ $$aCambridge, Mass.$$bCell Press$$c2016
000280487 3367_ $$2DRIVER$$aarticle
000280487 3367_ $$2DataCite$$aOutput Types/Journal article
000280487 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1471869823_7176
000280487 3367_ $$2BibTeX$$aARTICLE
000280487 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000280487 3367_ $$00$$2EndNote$$aJournal Article
000280487 520__ $$aThe assembly of clathrin triskelia into polyhedral cages during endocytosis is regulated by adaptor proteins (APs). We explore how APs achieve this by developing coarse-grained models for clathrin and AP2, employing a Monte Carlo click interaction, to simulate their collective aggregation behavior. The phase diagrams indicate that a crucial role is played by the mechanical properties of the disordered linker segment of AP. We also present a statistical-mechanical theory for the assembly behavior of clathrin, yielding good agreement with our simulations and experimental data from the literature. Adaptor proteins are found to regulate the formation of clathrin coats under certain conditions, but can also suppress the formation of cages.
000280487 536__ $$0G:(DE-HGF)POF3-551$$a551 - Functional Macromolecules and Complexes (POF3-551)$$cPOF3-551$$fPOF III$$x0
000280487 588__ $$aDataset connected to CrossRef
000280487 7001_ $$0P:(DE-HGF)0$$aden Otter, W. K.$$b1$$eCorresponding author
000280487 7001_ $$0P:(DE-Juel1)159317$$aBriels, Willem$$b2
000280487 773__ $$0PERI:(DE-600)1477214-0$$a10.1016/j.bpj.2016.06.003$$gVol. 111, no. 1, p. 222 - 235$$n1$$p222-235$$tBiophysical journal$$v111$$x0006-3495$$y2016
000280487 8564_ $$uhttps://juser.fz-juelich.de/record/280487/files/1-s2.0-S0006349516304052-main.pdf$$yRestricted
000280487 8564_ $$uhttps://juser.fz-juelich.de/record/280487/files/1-s2.0-S0006349516304052-main.gif?subformat=icon$$xicon$$yRestricted
000280487 8564_ $$uhttps://juser.fz-juelich.de/record/280487/files/1-s2.0-S0006349516304052-main.jpg?subformat=icon-1440$$xicon-1440$$yRestricted
000280487 8564_ $$uhttps://juser.fz-juelich.de/record/280487/files/1-s2.0-S0006349516304052-main.jpg?subformat=icon-180$$xicon-180$$yRestricted
000280487 8564_ $$uhttps://juser.fz-juelich.de/record/280487/files/1-s2.0-S0006349516304052-main.jpg?subformat=icon-640$$xicon-640$$yRestricted
000280487 8564_ $$uhttps://juser.fz-juelich.de/record/280487/files/1-s2.0-S0006349516304052-main.pdf?subformat=pdfa$$xpdfa$$yRestricted
000280487 909CO $$ooai:juser.fz-juelich.de:280487$$pVDB
000280487 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)159317$$aForschungszentrum Jülich GmbH$$b2$$kFZJ
000280487 9131_ $$0G:(DE-HGF)POF3-551$$1G:(DE-HGF)POF3-550$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lBioSoft – Fundamentals for future Technologies in the fields of Soft Matter and Life Sciences$$vFunctional Macromolecules and Complexes$$x0
000280487 9141_ $$y2016
000280487 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000280487 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences
000280487 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bBIOPHYS J : 2015
000280487 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000280487 915__ $$0StatID:(DE-HGF)0110$$2StatID$$aWoS$$bScience Citation Index
000280487 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000280487 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5
000280487 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000280487 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000280487 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000280487 915__ $$0StatID:(DE-HGF)0550$$2StatID$$aNo Authors Fulltext
000280487 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List
000280487 920__ $$lyes
000280487 9201_ $$0I:(DE-Juel1)ICS-3-20110106$$kICS-3$$lWeiche Materie $$x0
000280487 980__ $$ajournal
000280487 980__ $$aVDB
000280487 980__ $$aUNRESTRICTED
000280487 980__ $$aI:(DE-Juel1)ICS-3-20110106