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000282926 1001_ $$0P:(DE-Juel1)156207$$aKrämer, Christina$$b0$$ufzj
000282926 245__ $$aMikrobiologische Einzelzell-Phänotypencharakterisierung im Mikrochip
000282926 260__ $$aHeidelberg$$bSpektrum$$c2016
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000282926 520__ $$aMicrobes adapt to environmental changes by DNA embedded mechanisms (e. g. resistance) or non-DNA based phenotypical differentiation (e. g. tolerance). Single-cell fluorescence imaging combined with environmental control by microfluidic devices helps to unravel phenotypical changes of single microbial cells in isogenic cell populations. Therefore, the intracellular implementation of fluorescent molecules by genetic modification or dynamic staining is essential for non-invasive live-cell imaging.
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000282926 7001_ $$0P:(DE-Juel1)140195$$aKohlheyer, Dietrich$$b1$$eCorresponding author$$ufzj
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