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@ARTICLE{Gompper:283732,
author = {Gompper, Gerhard and Fedosov, Dmitry},
title = {{M}odeling microcirculatory blood flow: current state and
future perspectives},
journal = {Wiley interdisciplinary reviews / Systems biology and
medicine},
volume = {8},
number = {2},
issn = {1939-5094},
address = {Malden, MA},
publisher = {Wiley-Blackwell},
reportid = {FZJ-2016-02019},
pages = {157 - 168},
year = {2016},
abstract = {Microvascular blood flow determines a number of important
physiological processes of an organism in health and
disease. Therefore, a detailed understanding of
microvascular blood flow would significantly advance
biophysical and biomedical research and its applications.
Current developments in modeling of microcirculatory blood
flow already allow to go beyond available experimental
measurements and have a large potential to elucidate blood
flow behavior in normal and diseased microvascular networks.
There exist detailed models of blood flow on a single cell
level as well as simplified models of the flow through
microcirculatory networks, which are reviewed and discussed
here. The combination of these models provides promising
prospects for better understanding of blood flow behavior
and transport properties locally as well as globally within
large microvascular networks},
cin = {IAS-2 / ICS-2},
ddc = {610},
cid = {I:(DE-Juel1)IAS-2-20090406 / I:(DE-Juel1)ICS-2-20110106},
pnm = {553 - Physical Basis of Diseases (POF3-553)},
pid = {G:(DE-HGF)POF3-553},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000370644400004},
pubmed = {pmid:26695350},
doi = {10.1002/wsbm.1326},
url = {https://juser.fz-juelich.de/record/283732},
}