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@ARTICLE{Dombovari:29423,
      author       = {Dombovari, J. and Varga, Z. and Becker, J. S. and Matyus,
                      J. and Kakuk, G. and Papp, L.},
      title        = {{ICP}-{MS} determination of trace elements in the serum
                      samples of healthy subjects using different sample
                      preparation methods},
      journal      = {Atomic spectroscopy},
      volume       = {22},
      issn         = {0195-5373},
      address      = {Norwalk, Conn.},
      publisher    = {Perkin-Elmer},
      reportid     = {PreJuSER-29423},
      pages        = {331- 335},
      year         = {2001},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {The concentration of some trace elements of clinical
                      importance was studied in blood serum samples of healthy
                      subjects (n=19, mean age 22 +/- 4.5 years) to determine
                      reference ranges for the healthy urban population in Eastern
                      Hungary. A sample preparation method has been developed
                      using closed-vessel microwave digestion with an oxidizing
                      acid mixture (nitric acid and hydrogen peroxide) for
                      multielemental analysis and atmospheric wet digestion with
                      the aqueous solution of trimethyl amine (TMAH) for the
                      measurement of aluminum. Contamination of the samples with
                      Al was observed during acidic microwave digestion because of
                      the chemicals used. Trace element concentrations in the
                      samples were measured with ICP-TIS. The reference ranges
                      obtained were (in mug/L): Al 0.98-1.74, Cr 42.8-59.3, Mn
                      2.27-5.05, Fe 1282-2050, Co 0.22-0.88, Ni 0.03-16.33, Cu
                      691-1003, Zn 591-1217, Sr 30.37-47.37, Mo 0.73-1.19, Cd
                      0.02-0.62, and Pb 0.02-2.70. The results were compared to
                      the reference ranges actually used in the clinical practice,
                      some of which are available in the literature. The effect of
                      the applied digestion methods on the obtained individual
                      results and average concentration ranges was also studied.},
      keywords     = {J (WoSType)},
      cin          = {ZCH},
      ddc          = {530},
      cid          = {I:(DE-Juel1)ZCH-20090406},
      pnm          = {Entwicklung analytischer Verfahren},
      pid          = {G:(DE-Juel1)FUEK118},
      shelfmark    = {Spectroscopy},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000171404900001},
      url          = {https://juser.fz-juelich.de/record/29423},
}