TY  - JOUR
AU  - Csiszar, A.
AU  - Klumpp, E.
AU  - Bota, A.
AU  - Szegedi, K.
TI  - Effect of 2,4-dichlorophenol on DPPC/water liposomes studied by X-ray and freeze-fracture electron microscopy
JO  - Chemistry and physics of lipids
VL  - 126
SN  - 0009-3084
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - PreJuSER-32828
SP  - 155 - 166
PY  - 2003
N1  - Record converted from VDB: 12.11.2012
AB  - The effect of 2,4-dichlorophenol (DCP) was studied on the fully hydrated 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)-water liposomes. The structure and the thermotropic phase behaviour of the liposomes was examined in the presence of DCP (DCP/DPPC molar ratio, varied from 2 x 10(-2) up to 1) using small- and wide-angle X-ray scattering (SAXS, WAXS) and freeze-fracture electron microscopy. The structural behaviour of the DPPC/DCP/water system was strongly dependent on the concentration of the DCR In the pretransition range the DCP molecules (at 2 x 10(-2) DCP/DPPC molar ratio) induced the interdigitated phase beside the parent (gel and rippled gel) phases, locally which can be form at higher DCP concentration. When the DCP/DPPC molar ratio was increased the pretransition disappeared and the main transition was shifted to lower temperatures. In the molar ratio range from 2 x 10(-1) up to 5 x 10(-1), a coexistence of different phases was observed in the wide temperature range from 20 up to 40 degreesC. With a further increase of the DCP/DPPC molar ratio (6 x 10(-1) to 1) only the interdigitated gel phase occurred below 25 degreesC. A schematic phase diagram of DPPC/DCP/water system was constructed to summarise the results. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000187751700005
DO  - DOI:10.1016/j.chemphyslip.2003.08.005
UR  - https://juser.fz-juelich.de/record/32828
ER  -