TY  - JOUR
AU  - Maier, C. W.
AU  - Behrisch, A.
AU  - Kloboucek, A.
AU  - Simson, D. A.
AU  - Merkel, R.
TI  - Specific biomembrane adhesion-Indirect lateral interactions between bound receptor molecules
JO  - The European physical journal / E
VL  - 6
SN  - 1292-8941
CY  - Berlin
PB  - Springer
M1  - PreJuSER-3313
SP  - 273 - 276
PY  - 2001
N1  - Record converted from VDB: 12.11.2012
AB  - We studied biomembrane adhesion using the micropipet aspiration technique. Adhesion was caused by contact site A, a laterally mobile and highly specific cell adhesion molecule from Dictyostelium discoideum, reconstituted in lipid vesicles of DOPC (L-alpha-dioleoylphosphatidylcholine) with an addition of 5 mol % DOPE-PEG(2000) (1,2-diacyl-sn-glycero-3-phosphatidylethanolamine-N-[poly(ethyleneglycol) 2000]). The "fuzzy" membrane mimics the cellular plasma membrane including the glycocalyx. We found adhesion and subsequent receptor migration into the contact zone. Using membrane tension jumps to probe the equation of state of the two-dimensional "gas" of bound receptor pairs within the contact zone, we found strong, attractive lateral interactions.
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000173840600001
DO  - DOI:10.1007/s10189-001-8041-9
UR  - https://juser.fz-juelich.de/record/3313
ER  -