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@ARTICLE{Allahyarov:33766,
author = {Allahyarov, E. and Löwen, H. and Gompper, G.},
title = {{A}dsorption of monovalent and multivalent cations and
anions on {DNA} molecules},
journal = {Physical review / E},
volume = {68},
number = {6},
issn = {1063-651X},
address = {College Park, Md.},
publisher = {APS},
reportid = {PreJuSER-33766},
pages = {061903},
year = {2003},
note = {Record converted from VDB: 12.11.2012},
abstract = {Adsorption of monovalent and multivalent cations and anions
on a deoxyribose nucleic acid (DNA) molecule from a salt
solution is investigated by computer simulation. The ions
are modeled as charged hard spheres, the DNA molecule as a
point charge pattern following the double-helical phosphate
strands. The geometrical shape of the DNA molecules is
modeled on different levels ranging from a simple
cylindrical shape to structured models which include the
major and minor grooves between the phosphate strands. The
densities of the ions adsorbed on the phosphate strands in
the major and in the minor grooves are calculated. First, we
find that the adsorption pattern on the DNA surface depends
strongly on its geometrical shape: counterions adsorb
preferentially along the phosphate strands for a cylindrical
model shape, but in the minor groove for a geometrically
structured model. Second, we find that an addition of
monovalent salt ions results in an increase of the charge
density in the minor groove while the total charge density
of ions adsorbed in the major groove stays unchanged. The
adsorbed ion densities are highly structured along the minor
groove while they are almost smeared along the major groove.
Furthermore, for a fixed amount of added salt, the
major-groove cationic charge is independent of the
counterion valency. For increasing salt concentration the
major groove is neutralized while the total charge adsorbed
in the minor groove is constant. DNA overcharging is
detected for multivalent salts. Simulations for larger ion
radii, which mimic the effect of ion hydration, indicate an
increased adsorbtion of cations in the major groove.},
keywords = {J (WoSType)},
cin = {IFF-TH-II},
ddc = {530},
cid = {I:(DE-Juel1)VDB31},
pnm = {Kondensierte Materie},
pid = {G:(DE-Juel1)FUEK242},
shelfmark = {Physics, Fluids $\&$ Plasmas / Physics, Mathematical},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000188316600063},
doi = {10.1103/PhysRevE.68.061903},
url = {https://juser.fz-juelich.de/record/33766},
}