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| Home > Publications database > Ligand binding mode of GABA(A) receptor-associated protein > print |
| 001 | 344 | ||
| 005 | 20200402205337.0 | ||
| 024 | 7 | _ | |2 pmid |a pmid:18638487 |
| 024 | 7 | _ | |2 DOI |a 10.1016/j.jmb.2008.06.086 |
| 024 | 7 | _ | |2 WOS |a WOS:000259169100019 |
| 037 | _ | _ | |a PreJuSER-344 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 570 |
| 084 | _ | _ | |2 WoS |a Biochemistry & Molecular Biology |
| 100 | 1 | _ | |0 P:(DE-Juel1)131988 |a Weiergräber, O. H. |b 0 |u FZJ |
| 245 | _ | _ | |a Ligand binding mode of GABA(A) receptor-associated protein |
| 260 | _ | _ | |a Amsterdam [u.a.] |b Elsevier |c 2008 |
| 300 | _ | _ | |a 1320 - 1331 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |0 3552 |a Journal of Molecular Biology |v 381 |x 0022-2836 |
| 500 | _ | _ | |a The authors wish to thank Joachim Granzin for helpful discussion and Olga Dietz for excellent technical assistance. O.H.W. is grateful to Georg Buldt for continuous generous support. Moreover, assistance by the ESRF staff at beamline ID14-1 is acknowledged. This study was supported by a research grant from the Deutsche Forschungsgemeinschaft to D.W. (Wi1472/5). |
| 520 | _ | _ | |a The gamma-aminobutyric acid type A (GABA(A)) receptor-associated protein is a versatile adaptor protein playing an important role in intracellular vesicle trafficking, particularly in neuronal cells. We present the X-ray structure of the soluble form of human GABA(A) receptor-associated protein complexed with a high-affinity synthetic peptide at 1.3 A resolution. The data shed light on the probable binding modes of key interaction partners, including the GABA(A) receptor and the cysteine protease Atg4. The resulting models provide a structural background for further investigation of the unique biological properties of this protein. |
| 536 | _ | _ | |0 G:(DE-Juel1)FUEK409 |2 G:(DE-HGF) |a Funktion und Dysfunktion des Nervensystems |c P33 |x 0 |
| 588 | _ | _ | |a Dataset connected to Web of Science, Pubmed |
| 650 | _ | 2 | |2 MeSH |a Adaptor Proteins, Signal Transducing: chemistry |
| 650 | _ | 2 | |2 MeSH |a Adaptor Proteins, Signal Transducing: metabolism |
| 650 | _ | 2 | |2 MeSH |a Humans |
| 650 | _ | 2 | |2 MeSH |a Kinetics |
| 650 | _ | 2 | |2 MeSH |a Ligands |
| 650 | _ | 2 | |2 MeSH |a Magnetic Resonance Spectroscopy |
| 650 | _ | 2 | |2 MeSH |a Microtubule-Associated Proteins: chemistry |
| 650 | _ | 2 | |2 MeSH |a Microtubule-Associated Proteins: metabolism |
| 650 | _ | 2 | |2 MeSH |a Models, Molecular |
| 650 | _ | 2 | |2 MeSH |a Peptides: metabolism |
| 650 | _ | 2 | |2 MeSH |a Protein Binding |
| 650 | _ | 2 | |2 MeSH |a Protein Structure, Secondary |
| 650 | _ | 2 | |2 MeSH |a Surface Plasmon Resonance |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Adaptor Proteins, Signal Transducing |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a GABARAP protein, human |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Ligands |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Microtubule-Associated Proteins |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Peptides |
| 650 | _ | 7 | |2 WoSType |a J |
| 653 | 2 | 0 | |2 Author |a GABARAP |
| 653 | 2 | 0 | |2 Author |a GABA(A) receptor |
| 653 | 2 | 0 | |2 Author |a synthetic peptide |
| 653 | 2 | 0 | |2 Author |a phage display |
| 653 | 2 | 0 | |2 Author |a X-ray crystallography |
| 700 | 1 | _ | |0 P:(DE-Juel1)VDB8627 |a Stangler, T. |b 1 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)VDB77156 |a Thielmann, Y. |b 2 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)132012 |a Mohrlüder, J. |b 3 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)VDB15437 |a Wiesehan, K. |b 4 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)132029 |a Willbold, D. |b 5 |u FZJ |
| 773 | _ | _ | |0 PERI:(DE-600)1355192-9 |a 10.1016/j.jmb.2008.06.086 |g Vol. 381, p. 1320 - 1331 |p 1320 - 1331 |q 381<1320 - 1331 |t Journal of molecular biology |v 381 |x 0022-2836 |y 2008 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1016/j.jmb.2008.06.086 |
| 909 | C | O | |o oai:juser.fz-juelich.de:344 |p VDB |
| 913 | 1 | _ | |0 G:(DE-Juel1)FUEK409 |a DE-HGF |b Gesundheit |k P33 |l Funktion und Dysfunktion des Nervensystems |v Funktion und Dysfunktion des Nervensystems |x 0 |
| 914 | 1 | _ | |y 2008 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0010 |a JCR/ISI refereed |
| 920 | 1 | _ | |0 I:(DE-Juel1)VDB805 |d 31.12.2008 |g INB |k INB-2 |l Molekulare Biophysik |x 0 |
| 970 | _ | _ | |a VDB:(DE-Juel1)100618 |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a ConvertedRecord |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a I:(DE-Juel1)ISB-2-20090406 |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a I:(DE-Juel1)ICS-6-20110106 |
| 981 | _ | _ | |a I:(DE-Juel1)IBI-7-20200312 |
| 981 | _ | _ | |a I:(DE-Juel1)ISB-2-20090406 |
| 981 | _ | _ | |a I:(DE-Juel1)ICS-6-20110106 |
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