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000035116 1001_ $$0P:(DE-HGF)0$$aJäncke, J. H. R.$$b0
000035116 245__ $$aThe time course of the BOLD response in the human auditory cortex to acoustic stimuli of different duration
000035116 260__ $$aAmsterdam [u.a.]$$bElsevier Science Publ.$$c1999
000035116 29510 $$aCognitive Brain Research Volume 8, Issue 2, 16 July 1999, Pages 117-124
000035116 300__ $$a117 - 124
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000035116 520__ $$aThe relationship between activity within the human auditory cortices and the duration of heard tones was investigated by measuring the hemodynamic response with functional magnetic resonance imaging. We demonstrate that there is no significant influence of stimulus duration as used here on the intensity and spatial extent of the hemodynamic response in the auditory cortices. We found however, that the time course of the hemodynamic response to the repeated stimulus presentation exhibited a characteristic decline after the first stimulus exposure during the activation period. The possible reasons for this time course are currently unknown, however, several factors may be involved, including top-down mechanisms and/or the interplay of tissue perfusion and oxygen consumption.
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000035116 650_7 $$afMRI
000035116 650_7 $$aStimulus duration
000035116 650_7 $$aAuditory cortex
000035116 7001_ $$0P:(DE-HGF)0$$aBuchanan, T.$$b1
000035116 7001_ $$0P:(DE-HGF)0$$aLutz, K.$$b2
000035116 7001_ $$0P:(DE-Juel1)VDB1551$$aSpecht, K.$$b3$$uFZJ
000035116 7001_ $$0P:(DE-HGF)0$$aMirzazade, S.$$b4
000035116 7001_ $$0P:(DE-Juel1)131794$$aShah, J. N.$$b5$$uFZJ
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