000003689 001__ 3689
000003689 005__ 20180208224132.0
000003689 0247_ $$2pmid$$apmid:19729327
000003689 0247_ $$2DOI$$a10.1016/j.jmr.2009.08.004
000003689 0247_ $$2WOS$$aWOS:000271071400013
000003689 037__ $$aPreJuSER-3689
000003689 041__ $$aeng
000003689 082__ $$a610
000003689 084__ $$2WoS$$aBiochemical Research Methods
000003689 084__ $$2WoS$$aPhysics, Atomic, Molecular & Chemical
000003689 084__ $$2WoS$$aSpectroscopy
000003689 1001_ $$0P:(DE-HGF)0$$aAmor, N.$$b0
000003689 245__ $$aMagnetic resonance imaging of dissolved hyperpolarized 129Xe using a membrane-based continuous flow system
000003689 260__ $$aNew York, NY$$bWiley-Liss$$c2009
000003689 300__ $$a93 - 99
000003689 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000003689 3367_ $$2DataCite$$aOutput Types/Journal article
000003689 3367_ $$00$$2EndNote$$aJournal Article
000003689 3367_ $$2BibTeX$$aARTICLE
000003689 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000003689 3367_ $$2DRIVER$$aarticle
000003689 440_0 $$09910$$aJournal of Magnetic Resonance Imaging$$v201$$x1053-1807$$y1
000003689 500__ $$aWe thank S. Appelt and W. Hosing (FZ Julich) for the development of the xenon polarizer and H.-D. Lemke (Membrana GrnbH) for the oxygenator fiber membranes. This work was supported by the Kompetenznetz Asthma/COPD (competence network for Asthma/COPD) funded by the Federal Ministry of Education and Research (FKZ01 GI 0868-0872) and the MAIFOR program of the Johannes Gutenberg University.
000003689 520__ $$aA technique for continuous production of solutions containing hyperpolarized (129)Xe is explored for MRI applications. The method is based on hollow fiber membranes which inhibit the formation of foams and bubbles. A systematic analysis of various carrier agents for hyperpolarized (129)Xe has been carried out, which are applicable as contrast agents for in vivo MRI. The image quality of different hyperpolarized Xe solutions is compared and MRI results obtained in a clinical as well as in a nonclinical MRI setting are provided. Moreover, we demonstrate the application of (129)Xe contrast agents produced with our dissolution method for lung MRI by imaging hyperpolarized (129)Xe that has been both dissolved in and outgassed from a carrier liquid in a lung phantom, illustrating its potential for the measurement of lung perfusion and ventilation.
000003689 536__ $$0G:(DE-Juel1)FUEK407$$2G:(DE-HGF)$$aTerrestrische Umwelt$$cP24$$x0
000003689 588__ $$aDataset connected to Web of Science, Pubmed
000003689 65320 $$2Author$$aHyperpolarization
000003689 65320 $$2Author$$aXenon
000003689 65320 $$2Author$$aNMR
000003689 65320 $$2Author$$aMRI
000003689 65320 $$2Author$$aDissolution technique
000003689 65320 $$2Author$$aContrast agent
000003689 650_2 $$2MeSH$$aBiocompatible Materials
000003689 650_2 $$2MeSH$$aImage Processing, Computer-Assisted
000003689 650_2 $$2MeSH$$aLung: anatomy & histology
000003689 650_2 $$2MeSH$$aLung: chemistry
000003689 650_2 $$2MeSH$$aLung: physiology
000003689 650_2 $$2MeSH$$aMagnetic Resonance Imaging: methods
000003689 650_2 $$2MeSH$$aMembranes, Artificial
000003689 650_2 $$2MeSH$$aPhantoms, Imaging
000003689 650_2 $$2MeSH$$aPulmonary Circulation: physiology
000003689 650_2 $$2MeSH$$aRespiratory Mechanics
000003689 650_2 $$2MeSH$$aSolutions
000003689 650_2 $$2MeSH$$aXenon Isotopes: chemistry
000003689 650_7 $$00$$2NLM Chemicals$$aBiocompatible Materials
000003689 650_7 $$00$$2NLM Chemicals$$aMembranes, Artificial
000003689 650_7 $$00$$2NLM Chemicals$$aSolutions
000003689 650_7 $$00$$2NLM Chemicals$$aXenon Isotopes
000003689 650_7 $$2WoSType$$aJ
000003689 7001_ $$0P:(DE-HGF)0$$aZänker, P.P.$$b1
000003689 7001_ $$0P:(DE-Juel1)VDB49819$$aBlümler, P.$$b2$$uFZJ
000003689 7001_ $$0P:(DE-HGF)0$$aMeise, F.$$b3
000003689 7001_ $$0P:(DE-HGF)0$$aSchreiber, W.G.$$b4
000003689 7001_ $$0P:(DE-HGF)0$$aScholz, A.$$b5
000003689 7001_ $$0P:(DE-HGF)0$$aSchmiedeskamp, J.$$b6
000003689 7001_ $$0P:(DE-HGF)0$$aSpiess, H.W.$$b7
000003689 7001_ $$0P:(DE-HGF)0$$aMünnemann, K.$$b8
000003689 773__ $$0PERI:(DE-600)1497154-9$$a10.1016/j.jmr.2009.08.004$$gVol. 201, p. 93 - 99$$p93 - 99$$q201<93 - 99$$tJournal of magnetic resonance imaging$$v201$$x1053-1807$$y2009
000003689 8567_ $$uhttp://dx.doi.org/10.1016/j.jmr.2009.08.004
000003689 909CO $$ooai:juser.fz-juelich.de:3689$$pVDB
000003689 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000003689 9141_ $$aNachtrag$$y2009
000003689 9131_ $$0G:(DE-Juel1)FUEK407$$aDE-HGF$$bErde und Umwelt$$kP24$$lTerrestrische Umwelt$$vTerrestrische Umwelt$$x0
000003689 9201_ $$0I:(DE-Juel1)ICG-3-20090406$$d31.10.2010$$gICG$$kICG-3$$lPhytosphäre$$x1
000003689 970__ $$aVDB:(DE-Juel1)109977
000003689 980__ $$aVDB
000003689 980__ $$aConvertedRecord
000003689 980__ $$ajournal
000003689 980__ $$aI:(DE-Juel1)IBG-2-20101118
000003689 980__ $$aUNRESTRICTED
000003689 981__ $$aI:(DE-Juel1)IBG-2-20101118
000003689 981__ $$aI:(DE-Juel1)ICG-3-20090406