001     3689
005     20180208224132.0
024 7 _ |2 pmid
|a pmid:19729327
024 7 _ |2 DOI
|a 10.1016/j.jmr.2009.08.004
024 7 _ |2 WOS
|a WOS:000271071400013
037 _ _ |a PreJuSER-3689
041 _ _ |a eng
082 _ _ |a 610
084 _ _ |2 WoS
|a Biochemical Research Methods
084 _ _ |2 WoS
|a Physics, Atomic, Molecular & Chemical
084 _ _ |2 WoS
|a Spectroscopy
100 1 _ |0 P:(DE-HGF)0
|a Amor, N.
|b 0
245 _ _ |a Magnetic resonance imaging of dissolved hyperpolarized 129Xe using a membrane-based continuous flow system
260 _ _ |a New York, NY
|b Wiley-Liss
|c 2009
300 _ _ |a 93 - 99
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
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336 7 _ |a Output Types/Journal article
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336 7 _ |a Journal Article
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336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |0 9910
|a Journal of Magnetic Resonance Imaging
|v 201
|x 1053-1807
|y 1
500 _ _ |a We thank S. Appelt and W. Hosing (FZ Julich) for the development of the xenon polarizer and H.-D. Lemke (Membrana GrnbH) for the oxygenator fiber membranes. This work was supported by the Kompetenznetz Asthma/COPD (competence network for Asthma/COPD) funded by the Federal Ministry of Education and Research (FKZ01 GI 0868-0872) and the MAIFOR program of the Johannes Gutenberg University.
520 _ _ |a A technique for continuous production of solutions containing hyperpolarized (129)Xe is explored for MRI applications. The method is based on hollow fiber membranes which inhibit the formation of foams and bubbles. A systematic analysis of various carrier agents for hyperpolarized (129)Xe has been carried out, which are applicable as contrast agents for in vivo MRI. The image quality of different hyperpolarized Xe solutions is compared and MRI results obtained in a clinical as well as in a nonclinical MRI setting are provided. Moreover, we demonstrate the application of (129)Xe contrast agents produced with our dissolution method for lung MRI by imaging hyperpolarized (129)Xe that has been both dissolved in and outgassed from a carrier liquid in a lung phantom, illustrating its potential for the measurement of lung perfusion and ventilation.
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|2 G:(DE-HGF)
|a Terrestrische Umwelt
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|x 0
588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Biocompatible Materials
650 _ 2 |2 MeSH
|a Image Processing, Computer-Assisted
650 _ 2 |2 MeSH
|a Lung: anatomy & histology
650 _ 2 |2 MeSH
|a Lung: chemistry
650 _ 2 |2 MeSH
|a Lung: physiology
650 _ 2 |2 MeSH
|a Magnetic Resonance Imaging: methods
650 _ 2 |2 MeSH
|a Membranes, Artificial
650 _ 2 |2 MeSH
|a Phantoms, Imaging
650 _ 2 |2 MeSH
|a Pulmonary Circulation: physiology
650 _ 2 |2 MeSH
|a Respiratory Mechanics
650 _ 2 |2 MeSH
|a Solutions
650 _ 2 |2 MeSH
|a Xenon Isotopes: chemistry
650 _ 7 |0 0
|2 NLM Chemicals
|a Biocompatible Materials
650 _ 7 |0 0
|2 NLM Chemicals
|a Membranes, Artificial
650 _ 7 |0 0
|2 NLM Chemicals
|a Solutions
650 _ 7 |0 0
|2 NLM Chemicals
|a Xenon Isotopes
650 _ 7 |2 WoSType
|a J
653 2 0 |2 Author
|a Hyperpolarization
653 2 0 |2 Author
|a Xenon
653 2 0 |2 Author
|a NMR
653 2 0 |2 Author
|a MRI
653 2 0 |2 Author
|a Dissolution technique
653 2 0 |2 Author
|a Contrast agent
700 1 _ |0 P:(DE-HGF)0
|a Zänker, P.P.
|b 1
700 1 _ |0 P:(DE-Juel1)VDB49819
|a Blümler, P.
|b 2
|u FZJ
700 1 _ |0 P:(DE-HGF)0
|a Meise, F.
|b 3
700 1 _ |0 P:(DE-HGF)0
|a Schreiber, W.G.
|b 4
700 1 _ |0 P:(DE-HGF)0
|a Scholz, A.
|b 5
700 1 _ |0 P:(DE-HGF)0
|a Schmiedeskamp, J.
|b 6
700 1 _ |0 P:(DE-HGF)0
|a Spiess, H.W.
|b 7
700 1 _ |0 P:(DE-HGF)0
|a Münnemann, K.
|b 8
773 _ _ |0 PERI:(DE-600)1497154-9
|a 10.1016/j.jmr.2009.08.004
|g Vol. 201, p. 93 - 99
|p 93 - 99
|q 201<93 - 99
|t Journal of magnetic resonance imaging
|v 201
|x 1053-1807
|y 2009
856 7 _ |u http://dx.doi.org/10.1016/j.jmr.2009.08.004
909 C O |o oai:juser.fz-juelich.de:3689
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914 1 _ |a Nachtrag
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915 _ _ |0 StatID:(DE-HGF)0010
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981 _ _ |a I:(DE-Juel1)ICG-3-20090406


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