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@ARTICLE{Nyquist:38377,
      author       = {Nyquist, R. M. and Ataka, K. and Heberle, J.},
      title        = {{T}he molecular mechanism of membrane proteins probed by
                      evanescent infrared waves},
      journal      = {ChemBioChem},
      volume       = {5},
      issn         = {1439-4227},
      address      = {Weinheim},
      publisher    = {Wiley-VCH},
      reportid     = {PreJuSER-38377},
      pages        = {431 - 436},
      year         = {2004},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {The catalytic action of membrane proteins is vital to many
                      cellular processes. Yet the molecular mechanisms remain
                      poorly understood. We describe here the technique of
                      evanescent infrared difference spectroscopy as a tool to
                      decipher the structural changes associated with the
                      enzymatic action of membrane proteins. Functional changes as
                      minute as the protonation state of individual amino acid
                      side chains can be observed and linked to interactions with
                      a ligand, agonist, effector, or redox partner.},
      keywords     = {Bacteriorhodopsins: chemistry / Bacteriorhodopsins:
                      metabolism / Electron Transport Complex IV: chemistry /
                      Electron Transport Complex IV: metabolism / Membrane
                      Proteins: chemistry / Membrane Proteins: metabolism /
                      Rhodopsin: chemistry / Rhodopsin: metabolism /
                      Spectrophotometry, Infrared: methods / Membrane Proteins
                      (NLM Chemicals) / Bacteriorhodopsins (NLM Chemicals) /
                      Rhodopsin (NLM Chemicals) / Electron Transport Complex IV
                      (NLM Chemicals) / J (WoSType)},
      cin          = {IBI-2},
      ddc          = {540},
      cid          = {I:(DE-Juel1)VDB58},
      pnm          = {Neurowissenschaften},
      pid          = {G:(DE-Juel1)FUEK255},
      shelfmark    = {Biochemistry $\&$ Molecular Biology / Chemistry, Medicinal},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:15185365},
      UT           = {WOS:000220773500004},
      doi          = {10.1002/cbic.200300687},
      url          = {https://juser.fz-juelich.de/record/38377},
}