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@ARTICLE{Lettinga:38569,
author = {Lettinga, M. P. and Koenderink, G. H. and Kuipers, B. W. M.
and Bessels, E. and Philipse, R. H.},
title = {{R}otational dynamics of colloidal spheresprobed with
fluorescence recovery after photobleaching},
journal = {The journal of chemical physics},
volume = {120},
issn = {0021-9606},
address = {Melville, NY},
publisher = {American Institute of Physics},
reportid = {PreJuSER-38569},
pages = {4517 - 4529},
year = {2004},
note = {Record converted from VDB: 12.11.2012},
abstract = {We report a polarized fluorescence recovery after
photobleaching (pFRAP) method to measure the rotational
dynamics of fluorescent colloids over a wide dynamic range.
The method is based on the polarization anisotropy in the
fluorescence intensity, generated by bleaching of
fluorescently labeled particles with an intense pulse of
linearly polarized laser light. The rotational mobilities of
the fluorescent particles can be extracted from the
relaxation kinetics of the postbleach fluorescence
polarization anisotropy. Our pFRAP setup has access to
correlation times over a range of time scales from tens of
microseconds to tens of seconds, and is highly sensitive, so
very low concentrations of labeled particles can be probed.
We present a detailed description of the theoretical
background of pFRAP. The performance of the equipment is
demonstrated for fluorescent colloidal silica spheres,
dispersed in pure solvents as well as in fd-virus
suspensions.},
keywords = {Biomechanics / Colloids: analysis / Colloids: chemistry /
Computer Simulation / Diffusion / Fluorescence Recovery
After Photobleaching: methods / Microspheres / Models,
Chemical / Models, Molecular / Molecular Conformation /
Rotation / Stress, Mechanical / Colloids (NLM Chemicals) / J
(WoSType)},
cin = {IFF-IWM},
ddc = {540},
cid = {I:(DE-Juel1)VDB343},
pnm = {Kondensierte Materie},
pid = {G:(DE-Juel1)FUEK242},
shelfmark = {Physics, Atomic, Molecular $\&$ Chemical},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:15268620},
UT = {WOS:000189209200050},
doi = {10.1063/1.1644799},
url = {https://juser.fz-juelich.de/record/38569},
}