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001     45393
005     20200423204109.0
024 7 _ |a 10.1149/1.1865592
|2 DOI
024 7 _ |a WOS:000228326500006
|2 WOS
024 7 _ |a 1099-0062
|2 ISSN
024 7 _ |a 1944-8775
|2 ISSN
024 7 _ |a 2128/2882
|2 Handle
037 _ _ |a PreJuSER-45393
041 _ _ |a eng
082 _ _ |a 540
084 _ _ |2 WoS
|a Electrochemistry
084 _ _ |2 WoS
|a Materials Science, Multidisciplinary
100 1 _ |a Schober, T.
|b 0
|u FZJ
|0 P:(DE-Juel1)VDB3067
245 _ _ |a Composites of ceramic high-temperature proton conductors with inorganic compounds
260 _ _ |a Pennington, NJ
|b Soc.
|c 2005
300 _ _ |a A199 - A200
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|0 0
|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |a Electrochemical and Solid State Letters
|x 1099-0062
|0 13562
|y 4
|v 8
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a This open-label extension evaluated the long-term efficacy and tolerability of rufinamide in patients with Lennox-Gastaut syndrome (LGS) who had previously completed a 12-week double-blind study.In total, 124 patients (aged 4-37 years), receiving 1-3 concomitant antiepileptic drugs, were treated with rufinamide approximately 25-60 mg/kg/day. Efficacy was assessed by seizure frequency; tolerability by adverse events (AEs) and laboratory tests.Overall, patients were treated with rufinamide for a median (range) of 432 (10-1149) days. Reductions in seizure frequency were observed throughout the study; during the last 12 months of treatment, 41.0% and 47.9% of patients had > or = 50% reduction in total and tonic-atonic seizure frequency, respectively. The most common AEs were vomiting (30.6%) and pyrexia (25.8%).In this open-label extension, rufinamide appeared to be an effective long-term adjunctive therapy for the treatment of LGS-associated seizures in children and young adults.
536 _ _ |a Kondensierte Materie
|c M02
|2 G:(DE-HGF)
|0 G:(DE-Juel1)FUEK242
|x 0
588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 7 |a J
|2 WoSType
773 _ _ |a 10.1149/1.1865592
|g Vol. 8, p. A199 - A200
|p A199 - A200
|q 8|0 PERI:(DE-600)1483551-4
|t Electrochemical and solid-state letters
|v 8
|y 2005
|x 1099-0062
856 7 _ |u http://dx.doi.org/10.1149/1.1865592
|u http://hdl.handle.net/2128/2882
856 4 _ |u https://juser.fz-juelich.de/record/45393/files/68987.pdf
|y OpenAccess
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856 4 _ |u https://juser.fz-juelich.de/record/45393/files/68987.jpg?subformat=icon-640
|x icon-640
|y OpenAccess
909 C O |o oai:juser.fz-juelich.de:45393
|p openaire
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913 1 _ |k M02
|v Kondensierte Materie
|l Kondensierte Materie
|b Materie
|0 G:(DE-Juel1)FUEK242
|x 0
914 1 _ |y 2005
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
915 _ _ |2 StatID
|0 StatID:(DE-HGF)0510
|a OpenAccess
920 1 _ |k IFF-IEM
|l Elektronische Materialien
|d 31.12.2006
|g IFF
|0 I:(DE-Juel1)VDB321
|x 0
970 _ _ |a VDB:(DE-Juel1)68987
980 _ _ |a VDB
980 _ _ |a JUWEL
980 _ _ |a ConvertedRecord
980 _ _ |a journal
980 _ _ |a I:(DE-Juel1)PGI-7-20110106
980 _ _ |a UNRESTRICTED
980 _ _ |a FullTexts
980 1 _ |a FullTexts
981 _ _ |a I:(DE-Juel1)PGI-7-20110106

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