TY - JOUR
AU - Sambeth, R.
AU - Baumgärtner, A.
TI - Autocatalytic polymerization generates persistent random walk of crawling cells
JO - Physical review letters
VL - 86
SN - 0031-9007
CY - College Park, Md.
PB - APS
M1 - PreJuSER-46842
SP - 22
PY - 2001
N1 - Record converted from VDB: 12.11.2012
AB - The autocatalytic polymerization kinetics of the cytoskeletal actin network provides the basic mechanism for a persistent random walk of a crawling cell. It is shown that network remodeling by branching processes near the cell membrane is essential for the bimodal spatial stability of the network which induces a spontaneous breaking of isotropic cell motion. Details of the phenomena are analyzed using a simple polymerization model studied by analytical and simulation methods.
KW - J (WoSType)
LB - PUB:(DE-HGF)16
UR - <Go to ISI:>//WOS:000169013600055
DO - DOI:10.1103/PhysRevLett.86.5196
UR - https://juser.fz-juelich.de/record/46842
ER -