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@ARTICLE{Han:47543,
      author       = {Han, Y. and Offenhäusser, A. and Ingebrandt, S.},
      title        = {{D}etection of {DNA} hybridization by a field-effect
                      transistor with covalently attached catcher molecules},
      journal      = {Surface and interface analysis},
      volume       = {38},
      issn         = {0142-2421},
      address      = {Chichester [u.a.]},
      publisher    = {Wiley},
      reportid     = {PreJuSER-47543},
      pages        = {176 - 181},
      year         = {2006},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Electronic DNA sensors based on field-effect transistor
                      (FET) arrays operating in liquid environments offer an
                      alternative method for the detection of biomolecular binding
                      events without the requirement to label the analyte
                      molecules. In order to obtain reproducible signals from such
                      sensors, the attachment of the probe molecules to the gate
                      area of the transistor chips requires a well-controlled
                      supramolecular architecture. The FET chips used in this work
                      are non-metallized, 8-channel transistor devices with
                      micrometer dimensions of the gate structures, which are
                      encapsulated to be dipped into an analyte solution. Two
                      identical chips were functionalized with DNA catcher
                      molecules of different sequences and read out in a
                      differential measurement approach. In this article, we
                      describe the details of the surface modification and
                      covalent attachment of the catcher DNA. The surface
                      modification was characterized by XPS, Fourier transform
                      infrared spectroscopy (FT-IR), fluorescence microscopy and
                      imaging ellipsometry. Electrical FET recordings of the
                      immobilization and hybridization of DNA molecules are
                      presented. Copyright (C) 2006 John Wiley $\&$ Sons, Ltd.},
      keywords     = {J (WoSType)},
      cin          = {CNI / ISG-2 / JARA-FIT},
      ddc          = {540},
      cid          = {I:(DE-Juel1)VDB381 / I:(DE-Juel1)VDB42 /
                      $I:(DE-82)080009_20140620$},
      pnm          = {Grundlagen für zukünftige Informationstechnologien},
      pid          = {G:(DE-Juel1)FUEK412},
      shelfmark    = {Chemistry, Physical},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000237437100006},
      doi          = {10.1002/sia.2157},
      url          = {https://juser.fz-juelich.de/record/47543},
}