TY - JOUR
AU - Koenig, B. W.
AU - Gawrisch, K.
TI - Specific volumes of unsaturated phosphatidylcholines in the liquid crystalline lamellar phase
JO - Biochimica et biophysica acta / Biomembranes
VL - 1715
SN - 0005-2736
CY - Amsterdam
PB - Elsevier
M1 - PreJuSER-49118
SP - 65 - 70
PY - 2005
N1 - Record converted from VDB: 12.11.2012
AB - The specific volumes of seven 1,2-diacyl-sn-glycero-3-phosphocholines with symmetric, unbranched acyl chains containing one, four, or six cis double bonds per chain, or with a saturated sn-1 chain and one, four, or six cis double bonds in the sn-2 chain were determined by the neutral buoyancy method. Experiments were conducted in the liquid crystalline lamellar phase over the temperature range from 5 to 35 degrees C. It is demonstrated that the molecular volume of phosphatidylcholines can be well approximated as the sum of a constant volume of the polar lipid head region and the temperature-dependent volumes of hydrocarbon chain CH2, CH, and terminal CH3 groups. A linear dependence of chain segment volumes on temperature was observed. A self-consistent set of partially temperature-dependent volumes is obtained that allows prediction of phosphatidylcholine molecular volumes within very tight error margins.
KW - Chemistry, Physical
KW - Fatty Acids, Unsaturated: chemistry
KW - Membrane Lipids: chemistry
KW - Phosphatidylcholines: chemistry
KW - Physicochemical Phenomena
KW - Temperature
KW - Fatty Acids, Unsaturated (NLM Chemicals)
KW - Membrane Lipids (NLM Chemicals)
KW - Phosphatidylcholines (NLM Chemicals)
KW - J (WoSType)
LB - PUB:(DE-HGF)16
C6 - pmid:16109383
UR - <Go to ISI:>//WOS:000231586100008
DO - DOI:10.1016/j.bbamem.2005.07.006
UR - https://juser.fz-juelich.de/record/49118
ER -