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| Home > Publications database > Process Optimization of Continuous Gluconic Acid Fermentation by Isolated Yeast-Like Strains of Aureobasidium pullulans > print |
| 001 | 49745 | ||
| 005 | 20190625110330.0 | ||
| 024 | 7 | _ | |2 pmid |a pmid:15937884 |
| 024 | 7 | _ | |2 DOI |a 10.1002/bit.20533 |
| 024 | 7 | _ | |2 WOS |a WOS:000230915400012 |
| 024 | 7 | _ | |a altmetric:21814671 |2 altmetric |
| 037 | _ | _ | |a PreJuSER-49745 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 570 |
| 084 | _ | _ | |2 WoS |a Biotechnology & Applied Microbiology |
| 100 | 1 | _ | |a Anastassiadis, A. |b 0 |0 P:(DE-HGF)0 |
| 245 | _ | _ | |a Process Optimization of Continuous Gluconic Acid Fermentation by Isolated Yeast-Like Strains of Aureobasidium pullulans |
| 260 | _ | _ | |a New York, NY [u.a.] |b Wiley |c 2005 |
| 300 | _ | _ | |a 494 - 501 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |a Biotechnology and Bioengineering |x 0006-3592 |0 900 |y 4 |v 91 |
| 500 | _ | _ | |a Record converted from VDB: 12.11.2012 |
| 520 | _ | _ | |a This study was focused on the optimization of a new fermentation process for continuous gluconic acid production by the isolated yeast-like strain Aureobasidium pullulans DSM 7085 (isolate 70). Operational fermentation parameters were optimized in chemostat cultures, using a defined glucose medium. Different optima were found for growth and gluconic acid production for each set of operation parameters. Highest productivity was recorded at pH values between 6.5 and 7.0 and temperatures between 29 and 31 degrees C. A gluconic acid concentration higher than 230 g/L was continuously produced at residence times of 12 h. A steady state extracellular gluconic acid concentration of 234 g/L was measured at pH 6.5. 122% air saturation yielded the highest volumetric productivity and product concentration. The biomass-specific productivity increased steadily upon raising air saturation. An intracellular gluconic acid concentration of about 159 g/L (0.83 mol) was determined at 31 degrees C. This is to be compared with an extracellular concentration of 223 g/L (1.16 mol), which indicates the possible existence of an active transport system for gluconic acid secretion, or the presence of extracellular glucose oxidizing enzymes. The new process provides significant advantages over the traditional discontinuous fungi operations. The process control becomes easier, thus offering stable product quality and quantity. |
| 536 | _ | _ | |a Biotechnologie |c L02 |2 G:(DE-HGF) |0 G:(DE-Juel1)FUEK256 |x 0 |
| 588 | _ | _ | |a Dataset connected to Web of Science, Pubmed |
| 650 | _ | 2 | |2 MeSH |a Ascomycota: enzymology |
| 650 | _ | 2 | |2 MeSH |a Ascomycota: physiology |
| 650 | _ | 2 | |2 MeSH |a Bioreactors |
| 650 | _ | 2 | |2 MeSH |a Fermentation |
| 650 | _ | 2 | |2 MeSH |a Gluconates: metabolism |
| 650 | _ | 2 | |2 MeSH |a Hot Temperature |
| 650 | _ | 2 | |2 MeSH |a Humidity |
| 650 | _ | 2 | |2 MeSH |a Hydrogen-Ion Concentration |
| 650 | _ | 2 | |2 MeSH |a Microbiological Techniques: methods |
| 650 | _ | 2 | |2 MeSH |a Oxidation-Reduction |
| 650 | _ | 2 | |2 MeSH |a Oxygen: metabolism |
| 650 | _ | 7 | |0 0 |2 NLM Chemicals |a Gluconates |
| 650 | _ | 7 | |0 526-95-4 |2 NLM Chemicals |a gluconic acid |
| 650 | _ | 7 | |0 7782-44-7 |2 NLM Chemicals |a Oxygen |
| 650 | _ | 7 | |a J |2 WoSType |
| 653 | 2 | 0 | |2 Author |a continuous gluconic acid fermentation |
| 653 | 2 | 0 | |2 Author |a continuous fermentation |
| 653 | 2 | 0 | |2 Author |a gluconic acid |
| 653 | 2 | 0 | |2 Author |a Aureobasidium pullulans |
| 653 | 2 | 0 | |2 Author |a process development |
| 653 | 2 | 0 | |2 Author |a process optimization |
| 700 | 1 | _ | |a Aivasidis, A. |b 1 |0 P:(DE-HGF)0 |
| 700 | 1 | _ | |a Wandrey, C. |b 2 |u FZJ |0 P:(DE-Juel1)129071 |
| 700 | 1 | _ | |a Rehm, H.-J. |b 3 |0 P:(DE-HGF)0 |
| 773 | _ | _ | |a 10.1002/bit.20533 |g Vol. 91, p. 494 - 501 |p 494 - 501 |q 91<494 - 501 |0 PERI:(DE-600)1480809-2 |t Biotechnology & bioengineering |v 91 |y 2005 |x 0006-3592 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1002/bit.20533 |
| 909 | C | O | |o oai:juser.fz-juelich.de:49745 |p VDB |
| 913 | 1 | _ | |k L02 |v Biotechnologie |l Biotechnologie |b Leben |0 G:(DE-Juel1)FUEK256 |x 0 |
| 914 | 1 | _ | |y 2005 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0010 |a JCR/ISI refereed |
| 920 | 1 | _ | |k IBT-2 |l Biotechnologie 2 |g IBT |z ab 31.10.10 weitergeführt IBG-1 |0 I:(DE-Juel1)VDB56 |x 0 |
| 970 | _ | _ | |a VDB:(DE-Juel1)77822 |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a ConvertedRecord |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a I:(DE-Juel1)IBG-1-20101118 |
| 980 | _ | _ | |a UNRESTRICTED |
| 981 | _ | _ | |a I:(DE-Juel1)IBG-1-20101118 |
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