000050473 001__ 50473
000050473 005__ 20200423204316.0
000050473 0247_ $$2pmid$$apmid:16461729
000050473 0247_ $$2pmc$$apmc:PMC1392891
000050473 0247_ $$2DOI$$a10.1128/AEM.72.2.1688-1691.2006
000050473 0247_ $$2WOS$$aWOS:000235353100092
000050473 0247_ $$2Handle$$a2128/796
000050473 0247_ $$2altmetric$$aaltmetric:21814924
000050473 037__ $$aPreJuSER-50473
000050473 041__ $$aeng
000050473 082__ $$a570
000050473 084__ $$2WoS$$aBiotechnology & Applied Microbiology
000050473 084__ $$2WoS$$aMicrobiology
000050473 1001_ $$0P:(DE-Juel1)VDB940$$aLiebich, J.$$b0$$uFZJ
000050473 245__ $$aImprovement of Oligonucleotide Probe Design Criteria for Functional Gene Microarrays in Environmental applications
000050473 260__ $$aWashington, DC [u.a.]$$bSoc.$$c2006
000050473 300__ $$a1688 - 1691
000050473 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000050473 3367_ $$2DataCite$$aOutput Types/Journal article
000050473 3367_ $$00$$2EndNote$$aJournal Article
000050473 3367_ $$2BibTeX$$aARTICLE
000050473 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000050473 3367_ $$2DRIVER$$aarticle
000050473 440_0 $$08561$$aApplied and Environmental Microbiology$$v72$$x0099-2240$$y2
000050473 500__ $$aRecord converted from VDB: 12.11.2012
000050473 520__ $$aTo optimize oligonucleotide probe design criteria, PCR products with different similarities to probes were hybridized to a functional gene microarray designed to detect homologous genes from different organisms. In contrast to more restrictive probe designs based on a single criterion, simultaneous consideration of the percent similarity (< or =90%), the length of identical sequence stretches (< or =20 bases), and the binding free energy (> or =-35 kcal mol(-1)) was found to be predictive of probe specificity.
000050473 536__ $$0G:(DE-Juel1)FUEK407$$2G:(DE-HGF)$$aTerrestrische Umwelt$$cP24$$x0
000050473 588__ $$aDataset connected to Web of Science, Pubmed
000050473 650_2 $$2MeSH$$aBase Sequence
000050473 650_2 $$2MeSH$$aDrug Design
000050473 650_2 $$2MeSH$$aEnvironmental Microbiology
000050473 650_2 $$2MeSH$$aNucleic Acid Hybridization
000050473 650_2 $$2MeSH$$aOligonucleotide Array Sequence Analysis: methods
000050473 650_2 $$2MeSH$$aOligonucleotide Array Sequence Analysis: statistics & numerical data
000050473 650_2 $$2MeSH$$aOligonucleotide Probes: chemistry
000050473 650_2 $$2MeSH$$aOligonucleotide Probes: genetics
000050473 650_2 $$2MeSH$$aPolymerase Chain Reaction
000050473 650_2 $$2MeSH$$aThermodynamics
000050473 650_7 $$00$$2NLM Chemicals$$aOligonucleotide Probes
000050473 650_7 $$2WoSType$$aJ
000050473 7001_ $$0P:(DE-HGF)0$$aSchadt, C. W.$$b1
000050473 7001_ $$0P:(DE-HGF)0$$aChong, S. C.$$b2
000050473 7001_ $$0P:(DE-HGF)0$$aHe, Z.$$b3
000050473 7001_ $$0P:(DE-HGF)0$$aRhee, S.-K.$$b4
000050473 7001_ $$0P:(DE-HGF)0$$aZhou, J.-H.$$b5
000050473 773__ $$0PERI:(DE-600)1478346-0$$a10.1128/AEM.72.2.1688-1691.2006$$gVol. 72, p. 1688 - 1691$$p1688 - 1691$$q72<1688 - 1691$$tApplied and environmental microbiology$$v72$$x0099-2240$$y2006
000050473 8567_ $$2Pubmed Central$$uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1392891
000050473 8564_ $$uhttps://juser.fz-juelich.de/record/50473/files/78793.pdf$$yOpenAccess
000050473 8564_ $$uhttps://juser.fz-juelich.de/record/50473/files/78793.jpg?subformat=icon-1440$$xicon-1440$$yOpenAccess
000050473 8564_ $$uhttps://juser.fz-juelich.de/record/50473/files/78793.jpg?subformat=icon-180$$xicon-180$$yOpenAccess
000050473 8564_ $$uhttps://juser.fz-juelich.de/record/50473/files/78793.jpg?subformat=icon-640$$xicon-640$$yOpenAccess
000050473 909CO $$ooai:juser.fz-juelich.de:50473$$pdnbdelivery$$pVDB$$pdriver$$popen_access$$popenaire
000050473 9131_ $$0G:(DE-Juel1)FUEK407$$bErde und Umwelt$$kP24$$lTerrestrische Umwelt$$vTerrestrische Umwelt$$x0
000050473 9141_ $$y2006
000050473 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000050473 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000050473 9201_ $$0I:(DE-Juel1)VDB50$$d31.12.2006$$gICG$$kICG-IV$$lAgrosphäre$$x0
000050473 970__ $$aVDB:(DE-Juel1)78793
000050473 980__ $$aVDB
000050473 980__ $$aJUWEL
000050473 980__ $$aConvertedRecord
000050473 980__ $$ajournal
000050473 980__ $$aI:(DE-Juel1)IBG-3-20101118
000050473 980__ $$aUNRESTRICTED
000050473 980__ $$aFullTexts
000050473 9801_ $$aFullTexts
000050473 981__ $$aI:(DE-Juel1)IBG-3-20101118