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@ARTICLE{Kastenholz:50735,
author = {Kastenholz, B.},
title = {{I}mportant contributions of a new quantitative preparative
native continuous polyacrylamide gel electrophoresis
({QPNC}-{PAGE}) procedure for elucidating metal cofactor
metabolisms in protein-misfolding diseases - a theory},
journal = {Protein and peptide letters},
volume = {13},
issn = {0929-8665},
address = {Schiphol},
publisher = {Bentham Science Publ.},
reportid = {PreJuSER-50735},
pages = {503 - 508},
year = {2006},
note = {Record converted from VDB: 12.11.2012},
abstract = {The quantitative analysis of metallochaperone proteins in
biofluids (e.g. blood, liquor) may be a major prerequisite
for clinical investigations concerning the
structure-function relationships of biologically-active
metal cofactor-containing chaperones in protein-misfolding
diseases (e.g. Alzheimer's or related diseases). For these
purposes, a new state-of-the-art gel electrophoresis
[quantitative preparative native continuous polyacrylamide
gel electrophoresis procedure (QPNC-PAGE)] combined with
biological mass and NMR spectrometrics might essentially
contribute to provide fundamental insights into the
metabolisms of important metal cofactors in biological
systems and the proper folding of metallochaperones in
conformational diseases.},
keywords = {J (WoSType)},
cin = {ICG-III},
ddc = {540},
cid = {I:(DE-Juel1)VDB49},
pnm = {Terrestrische Umwelt},
pid = {G:(DE-Juel1)FUEK407},
shelfmark = {Biochemistry $\&$ Molecular Biology},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000237935900015},
doi = {10.2174/092986606776819637},
url = {https://juser.fz-juelich.de/record/50735},
}