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@ARTICLE{Ggelein:508,
author = {Gögelein, C. and Nägele, G. and Tuinier, R. and Gibaud,
T. and Stradner, A. and Schurtenberger, P.},
title = {{A} simple patchy colloid model for the phase behavior of
lysozyme dispersions},
journal = {The journal of chemical physics},
volume = {129},
issn = {0021-9606},
address = {Melville, NY},
publisher = {American Institute of Physics},
reportid = {PreJuSER-508},
pages = {085102},
year = {2008},
note = {This project has been partly supported by the European
Commission under the 6<SUP>th</SUP> Framework Program
through integrating and strengthening the European Research
Area. Contract No. SoftComp, NoE/NMP3-CT-2004-502235.},
abstract = {We propose a minimal model for spherical proteins with
aeolotopic pair interactions to describe the equilibrium
phase behavior of lysozyme. The repulsive screened Coulomb
interactions between the particles are taken into account
assuming that the net charges are smeared out homogeneously
over the spherical protein surfaces. We incorporate
attractive surface patches, with the interactions between
patches on different spheres modeled by an attractive Yukawa
potential. The parameters entering the attractive Yukawa
potential part are determined using information on the
experimentally accessed gas-liquid-like critical point. The
Helmholtz free energy of the fluid and solid phases is
calculated using second-order thermodynamic perturbation
theory. Our predictions for the solubility curve are in fair
agreement with experimental data. In addition, we present
new experimental data for the gas-liquid coexistence curves
at various salt concentrations and compare these with our
model calculations. In agreement with earlier findings, we
observe that the strength and the range of the attractive
potential part only weakly depend on the salt content.},
keywords = {Algorithms / Animals / Biophysics: methods / Chemistry,
Physical: methods / Chickens / Colloids: chemistry / Egg
Proteins: chemistry / Hydrogen-Ion Concentration / Models,
Statistical / Models, Theoretical / Muramidase: chemistry /
Solubility / Solvents: chemistry / Temperature /
Thermodynamics / Colloids (NLM Chemicals) / Egg Proteins
(NLM Chemicals) / Solvents (NLM Chemicals) / Muramidase (NLM
Chemicals) / J (WoSType)},
cin = {IFF-7},
ddc = {540},
cid = {I:(DE-Juel1)VDB787},
pnm = {Kondensierte Materie},
pid = {G:(DE-Juel1)FUEK414},
shelfmark = {Physics, Atomic, Molecular $\&$ Chemical},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:19044852},
UT = {WOS:000259008900044},
doi = {10.1063/1.2951987},
url = {https://juser.fz-juelich.de/record/508},
}