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@ARTICLE{Vliegenthart:52397,
author = {Vliegenthart, G. A. and Gompper, G.},
title = {{M}echanical {D}eformation of {S}pherical {V}iruses with
{I}cosahedral {S}ymmetry},
journal = {Biophysical journal},
volume = {91},
issn = {0006-3495},
address = {New York, NY},
publisher = {Rockefeller Univ. Press},
reportid = {PreJuSER-52397},
pages = {834 - 841},
year = {2006},
note = {Record converted from VDB: 12.11.2012},
abstract = {Virus capsids and crystalline surfactant vesicles are two
examples of self-assembled shells in the nano- to micrometer
size range. Virus capsids are particularly interesting since
they have to sustain large internal pressures while
encapsulating and protecting the viral DNA. We therefore
study the mechanical properties of crystalline shells of
icosahedral symmetry on a substrate under a uniaxial applied
force by computer simulations. We predict the elastic
response for small deformations, and the buckling
transitions at large deformations. Both are found to depend
strongly on the number of elementary building blocks N (the
capsomers in the case of viral shells), the Föppl-von
Kármán number gamma (which characterizes the relative
importance of shear and bending elasticity), and the
confining geometry. In particular, we show that whereas
large shells are well described by continuum
elasticity-theory, small shells of the size of typical viral
capsids behave differently already for small deformations.
Our results are essential to extract quantitative
information about the elastic properties of viruses and
vesicles from deformation experiments.},
keywords = {Biophysics: methods / Capsid: chemistry / Capsid Proteins /
Computer Simulation / Elasticity / Kinetics / Models,
Statistical / Virus Assembly / Virus Physiological Phenomena
/ Viruses: chemistry / Capsid Proteins (NLM Chemicals) / J
(WoSType)},
cin = {IFF-TH-II},
ddc = {570},
cid = {I:(DE-Juel1)VDB31},
pnm = {Kondensierte Materie},
pid = {G:(DE-Juel1)FUEK414},
shelfmark = {Biophysics},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:16679375},
pmc = {pmc:PMC1563762},
UT = {WOS:000239086800008},
doi = {10.1529/biophysj.106.081422},
url = {https://juser.fz-juelich.de/record/52397},
}