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@ARTICLE{Meier:53548,
author = {Meier, R. J. and Csiszár, A. and Klumpp, E.},
title = {{D}etecting the effect of very low amounts of penetrants in
lipid bilayers using {R}aman spectroscopy},
journal = {The journal of physical chemistry / B},
volume = {110},
issn = {1520-6106},
address = {Washington, DC},
publisher = {Soc.},
reportid = {PreJuSER-53548},
pages = {20727 - 20728},
year = {2006},
note = {Record converted from VDB: 12.11.2012},
abstract = {We show that, by the influence on the gauche content in the
acyl chains, the effect of very low concentrations (order
10(-2) $\%)$ of penetrants (here 2,4-dichlorophenol) in
lipid bilayers (here dipalmitoyl-glycerophosphatidylcholine)
can be experimentally seen in the Raman spectra. The
observed effects suggest increased order and are in
accordance with previous X-ray diffraction and calorimetric
data. These findings show great promise for studying in situ
the effect of low amounts of various small molecules on cell
membranes using Raman spectroscopy.},
keywords = {1,2-Dipalmitoylphosphatidylcholine / Lipid Bilayers:
metabolism / Organic Chemicals: pharmacokinetics /
Permeability: drug effects / Phase Transition: drug effects
/ Spectrum Analysis, Raman / Lipid Bilayers (NLM Chemicals)
/ Organic Chemicals (NLM Chemicals) /
1,2-Dipalmitoylphosphatidylcholine (NLM Chemicals) / J
(WoSType)},
cin = {ICG-IV / ISG-4},
ddc = {530},
cid = {I:(DE-Juel1)VDB50 / I:(DE-Juel1)VDB421},
pnm = {Terrestrische Umwelt / Kondensierte Materie},
pid = {G:(DE-Juel1)FUEK407 / G:(DE-Juel1)FUEK414},
shelfmark = {Chemistry, Physical},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:17048874},
UT = {WOS:000241381600001},
doi = {10.1021/jp0615757},
url = {https://juser.fz-juelich.de/record/53548},
}