001     53548
005     20200423204359.0
024 7 _ |a pmid:17048874
|2 pmid
024 7 _ |a 10.1021/jp0615757
|2 DOI
024 7 _ |a WOS:000241381600001
|2 WOS
024 7 _ |a 2128/799
|2 Handle
037 _ _ |a PreJuSER-53548
041 _ _ |a eng
082 _ _ |a 530
084 _ _ |2 WoS
|a Chemistry, Physical
100 1 _ |a Meier, R. J.
|b 0
|0 P:(DE-HGF)0
245 _ _ |a Detecting the effect of very low amounts of penetrants in lipid bilayers using Raman spectroscopy
260 _ _ |a Washington, DC
|b Soc.
|c 2006
300 _ _ |a 20727 - 20728
336 7 _ |a Journal Article
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336 7 _ |a JOURNAL_ARTICLE
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336 7 _ |a article
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440 _ 0 |a Journal of Physical Chemistry B
|x 1520-6106
|0 3694
|v 110
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a We show that, by the influence on the gauche content in the acyl chains, the effect of very low concentrations (order 10(-2) %) of penetrants (here 2,4-dichlorophenol) in lipid bilayers (here dipalmitoyl-glycerophosphatidylcholine) can be experimentally seen in the Raman spectra. The observed effects suggest increased order and are in accordance with previous X-ray diffraction and calorimetric data. These findings show great promise for studying in situ the effect of low amounts of various small molecules on cell membranes using Raman spectroscopy.
536 _ _ |a Terrestrische Umwelt
|c P24
|2 G:(DE-HGF)
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536 _ _ |a Kondensierte Materie
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588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a 1,2-Dipalmitoylphosphatidylcholine
650 _ 2 |2 MeSH
|a Lipid Bilayers: metabolism
650 _ 2 |2 MeSH
|a Organic Chemicals: pharmacokinetics
650 _ 2 |2 MeSH
|a Permeability: drug effects
650 _ 2 |2 MeSH
|a Phase Transition: drug effects
650 _ 2 |2 MeSH
|a Spectrum Analysis, Raman
650 _ 7 |0 0
|2 NLM Chemicals
|a Lipid Bilayers
650 _ 7 |0 0
|2 NLM Chemicals
|a Organic Chemicals
650 _ 7 |0 2644-64-6
|2 NLM Chemicals
|a 1,2-Dipalmitoylphosphatidylcholine
650 _ 7 |a J
|2 WoSType
700 1 _ |a Csiszár, A.
|b 1
|u FZJ
|0 P:(DE-Juel1)128805
700 1 _ |a Klumpp, E.
|b 2
|u FZJ
|0 P:(DE-Juel1)129484
773 _ _ |a 10.1021/jp0615757
|g Vol. 110, p. 20727 - 20728
|p 20727 - 20728
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|0 PERI:(DE-600)2006039-7
|t The @journal of physical chemistry / B
|v 110
|y 2006
|x 1520-6106
856 7 _ |u http://dx.doi.org/10.1021/jp0615757
|u http://hdl.handle.net/2128/799
856 4 _ |u https://juser.fz-juelich.de/record/53548/files/84105.pdf
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913 1 _ |k P54
|v Kondensierte Materie
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|z entfällt bis 2009
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914 1 _ |y 2006
915 _ _ |0 StatID:(DE-HGF)0010
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