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@ARTICLE{Biehl:541,
      author       = {Biehl, R. and Hoffmann, B. and Monkenbusch, M. and Falus,
                      P. and Préost, S. and Merkel, R. and Richter, D.},
      title        = {{D}irect {O}bservation of {C}orrelated {I}nterdomain
                      {M}otion in {A}lcohol {D}ehydrogenase},
      journal      = {Physical review letters},
      volume       = {101},
      issn         = {0031-9007},
      address      = {College Park, Md.},
      publisher    = {APS},
      reportid     = {PreJuSER-541},
      pages        = {138102-1 - 138102-4},
      year         = {2008},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Interdomain motions in proteins are essential to enable or
                      promote biochemical function. Neutron spinecho spectroscopy
                      is used to directly observe the domain dynamics of the
                      protein alcohol dehydrogenase. The collective motion of
                      domains as revealed by their coherent form factor relates to
                      the cleft opening dynamics between the binding and the
                      catalytic domains enabling binding and release of the
                      functional important cofactor. The cleft opening mode
                      hardens as a result of an overall stiffening of the domain
                      complex due to the binding of the cofactor.},
      keywords     = {J (WoSType)},
      cin          = {IBN-4 / IFF-5 / IFF-4 / Jülich Centre for Neutron Science
                      JCNS (JCNS) ; JCNS},
      ddc          = {550},
      cid          = {I:(DE-Juel1)VDB802 / I:(DE-Juel1)VDB785 /
                      I:(DE-Juel1)VDB784 / I:(DE-Juel1)JCNS-20121112},
      pnm          = {Kondensierte Materie / Großgeräte für die Forschung mit
                      Photonen, Neutronen und Ionen (PNI)},
      pid          = {G:(DE-Juel1)FUEK414 / G:(DE-Juel1)FUEK415},
      shelfmark    = {Physics, Multidisciplinary},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000259680600076},
      doi          = {10.1103/PhysRevLett.101.138102},
      url          = {https://juser.fz-juelich.de/record/541},
}