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| Home > Publications database > Direct Observation of Correlated Interdomain Motion in Alcohol Dehydrogenase > print |
| 001 | 541 | ||
| 005 | 20250129094234.0 | ||
| 024 | 7 | _ | |2 DOI |a 10.1103/PhysRevLett.101.138102 |
| 024 | 7 | _ | |2 WOS |a WOS:000259680600076 |
| 024 | 7 | _ | |2 Handle |a 2128/7176 |
| 037 | _ | _ | |a PreJuSER-541 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 550 |
| 084 | _ | _ | |2 WoS |a Physics, Multidisciplinary |
| 100 | 1 | _ | |0 P:(DE-Juel1)130542 |a Biehl, R. |b 0 |u FZJ |
| 245 | _ | _ | |a Direct Observation of Correlated Interdomain Motion in Alcohol Dehydrogenase |
| 260 | _ | _ | |a College Park, Md. |b APS |c 2008 |
| 300 | _ | _ | |a 138102-1 - 138102-4 |
| 336 | 7 | _ | |a Journal Article |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 440 | _ | 0 | |0 4925 |a Physical Review Letters |v 101 |x 0031-9007 |
| 500 | _ | _ | |a Record converted from VDB: 12.11.2012 |
| 520 | _ | _ | |a Interdomain motions in proteins are essential to enable or promote biochemical function. Neutron spinecho spectroscopy is used to directly observe the domain dynamics of the protein alcohol dehydrogenase. The collective motion of domains as revealed by their coherent form factor relates to the cleft opening dynamics between the binding and the catalytic domains enabling binding and release of the functional important cofactor. The cleft opening mode hardens as a result of an overall stiffening of the domain complex due to the binding of the cofactor. |
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| 700 | 1 | _ | |0 P:(DE-Juel1)VDB27696 |a Hoffmann, B. |b 1 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)VDB2684 |a Monkenbusch, M. |b 2 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-HGF)0 |a Falus, P. |b 3 |
| 700 | 1 | _ | |0 P:(DE-HGF)0 |a Préost, S. |b 4 |
| 700 | 1 | _ | |0 P:(DE-Juel1)128833 |a Merkel, R. |b 5 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)130917 |a Richter, D. |b 6 |u FZJ |
| 773 | _ | _ | |0 PERI:(DE-600)1472655-5 |a 10.1103/PhysRevLett.101.138102 |g Vol. 101, p. 138102-1 - 138102-4 |p 138102-1 - 138102-4 |q 101<138102-1 - 138102-4 |t Physical review letters |v 101 |x 0031-9007 |y 2008 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1103/PhysRevLett.101.138102 |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/541/files/FZJ-541.pdf |y OpenAccess |z Published final document. |
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| 913 | 1 | _ | |0 G:(DE-Juel1)FUEK414 |b Materie |k P54 |l Kondensierte Materie |v Kondensierte Materie |x 0 |z entfällt bis 2009 |
| 913 | 1 | _ | |0 G:(DE-Juel1)FUEK415 |b Struktur der Materie |k P55 |l Großgeräteforschung mit Photonen, Neutronen und Ionen |v Großgeräte für die Forschung mit Photonen, Neutronen und Ionen (PNI) |x 1 |
| 914 | 1 | _ | |y 2008 |
| 915 | _ | _ | |0 StatID:(DE-HGF)0010 |a JCR/ISI refereed |
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| 915 | _ | _ | |0 LIC:(DE-HGF)APS-112012 |2 HGFVOC |a American Physical Society Transfer of Copyright Agreement |
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| 920 | 1 | _ | |0 I:(DE-Juel1)VDB785 |d 31.12.2010 |g IFF |k IFF-5 |l Neutronenstreuung |x 1 |
| 920 | 1 | _ | |0 I:(DE-Juel1)VDB784 |d 31.12.2010 |g IFF |k IFF-4 |l Streumethoden |x 2 |
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