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@ARTICLE{Granzin:54327,
      author       = {Granzin, J. and Eckhoff, A. and Weiergräber, O. H.},
      title        = {{C}rystal structure of a multi-domain immunophilin from
                      {A}rabidopsis thaliana: {A} paradigm for regulation of plan
                      {ABC} transporters},
      journal      = {Journal of molecular biology},
      volume       = {364},
      issn         = {0022-2836},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {PreJuSER-54327},
      pages        = {799 - 809},
      year         = {2006},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {FKBP42 is a membrane-anchored immunophilin playing a
                      critical role in morphogenesis and development of higher
                      plants. We present the X-ray structure of the cytoplasmic
                      portion of FKBP42 comprising both the FKBP-like domain and
                      the TPR domain at 2.85 A resolution. The data shed light on
                      the probable binding modes of key interaction partners,
                      including HSP90 and two classes of ABC transporters. The
                      resulting models provide a structural background for further
                      investigation of the unique biological properties of this
                      protein.},
      keywords     = {ATP-Binding Cassette Transporters: metabolism / Arabidopsis
                      Proteins: chemistry / Crystallography, X-Ray / Cytoplasm /
                      HSP90 Heat-Shock Proteins: metabolism / Immunophilins:
                      chemistry / Molecular Structure / Protein Binding / Protein
                      Conformation / Tacrolimus Binding Proteins: chemistry /
                      ATP-Binding Cassette Transporters (NLM Chemicals) /
                      Arabidopsis Proteins (NLM Chemicals) / HSP90 Heat-Shock
                      Proteins (NLM Chemicals) / TWD1 protein, Arabidopsis (NLM
                      Chemicals) / Tacrolimus Binding Proteins (NLM Chemicals) /
                      Immunophilins (NLM Chemicals) / J (WoSType)},
      cin          = {IBI-2},
      ddc          = {570},
      cid          = {I:(DE-Juel1)VDB58},
      pnm          = {Funktion und Dysfunktion des Nervensystems},
      pid          = {G:(DE-Juel1)FUEK409},
      shelfmark    = {Biochemistry $\&$ Molecular Biology},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:17045295},
      UT           = {WOS:000242674200019},
      doi          = {10.1016/j.jmb.2006.09.052},
      url          = {https://juser.fz-juelich.de/record/54327},
}