TY  - JOUR
AU  - Agulles-Pedrós, L.
AU  - Acosta, R.H.
AU  - Blümler, P.
AU  - Spiess, H.W.
TI  - Resolution enhancement in MRI of laser polarized 3He by control of diffusion
JO  - Journal of magnetic resonance
VL  - 197
SN  - 1090-7807
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - PreJuSER-544
SP  - 56 - 62
PY  - 2009
N1  - The authors want to thank Manfred Hehn and Hanspeter Raich for their help in the design and construction of the gas handling system at the MPI-P and jorg Schmiecleskarnp for the <SUP>3</SUP>He hyperpolarization. Financial support by DFG (Forschergruppe "Bildgestatzte zeitliche und regionale Analyse der Ventilations - Peifusionsverhdltnisse in der Lunge", grant # FOR 474) and a special grant of the Max Planck society made this work possible. Finally, we want to acknowledge the Partner Group for NMR Spectroscopy with High Spin Polarization FaMAF-MPIP.
AB  - Diffusion of atoms or molecules in presence of magnetic field gradients not only attenuates the NMR signal but also leads to distortions close to restricting boundaries. This phenomenon is most evident in imaging with laser polarized (LP) noble gases. Diffusion of gases can be manipulated, however, by admixing inert gases of different molecular weight. In this work we analyze the effect of mixing LP-(3)He with SF(6) on the image quality of a phantom consisting of an arrangement of capillaries with different diameters. Admixing buffer gases of higher molecular weight changes the contrast and offers a means to record images with high spatial and time resolution. Additionally we demonstrate how distortions due to edge enhancement can be reduced even for long timed MRI-sequences.
KW  - Diffusion
KW  - Diffusion Magnetic Resonance Imaging: methods
KW  - Gases: chemistry
KW  - Gases: radiation effects
KW  - Helium: analysis
KW  - Helium: chemistry
KW  - Image Enhancement: methods
KW  - Isotopes: analysis
KW  - Isotopes: chemistry
KW  - Lasers
KW  - Magnetic Resonance Spectroscopy: methods
KW  - Gases (NLM Chemicals)
KW  - Isotopes (NLM Chemicals)
KW  - Helium (NLM Chemicals)
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:19128992
UR  - <Go to ISI:>//WOS:000263987500009
DO  - DOI:10.1016/j.jmr.2008.12.003
UR  - https://juser.fz-juelich.de/record/544
ER  -