TY  - JOUR
AU  - Kastenholz, B.
AU  - Garfin, D. E.
TI  - Medicinal Plants: A Natural Chaperones Source for Treating Neurological Disorders
JO  - Protein and peptide letters
VL  - 16
SN  - 0929-8665
CY  - Schiphol
PB  - Bentham Science Publ.
M1  - PreJuSER-552
SP  - 116 - 120
PY  - 2009
N1  - Record converted from VDB: 12.11.2012
AB  - Currently, no pharmaceuticals for the etiological treatment of neurodegenerative protein-misfolding diseases (e. g., ALS, Alzheimer's or prion diseases) are available. In this brief communication the development of chaperone-based medications from medicinal plants (e. g., Ginkgo biloba) are reviewed as referred to specific protein-protein interactions of plant metallochaperones and human enzymes. It is indicated that bioactive copper chaperones for superoxide dismutase isolated from medicinal plants may be lead molecules for drug development in several diseases concerning metal ion metabolisms of man and animals.
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000263980200003
DO  - DOI:10.2174/092986609787316234
UR  - https://juser.fz-juelich.de/record/552
ER  -