001     552
005     20190625110305.0
024 7 _ |2 DOI
|a 10.2174/092986609787316234
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037 _ _ |a PreJuSER-552
041 _ _ |a eng
082 _ _ |a 540
084 _ _ |2 WoS
|a Biochemistry & Molecular Biology
100 1 _ |a Kastenholz, B.
|b 0
|u FZJ
|0 P:(DE-Juel1)129343
245 _ _ |a Medicinal Plants: A Natural Chaperones Source for Treating Neurological Disorders
260 _ _ |a Schiphol
|b Bentham Science Publ.
|c 2009
300 _ _ |a 116 - 120
336 7 _ |a Journal Article
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336 7 _ |a article
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440 _ 0 |a Protein and Peptide Letters
|x 0929-8665
|0 15161
|v 16
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a Currently, no pharmaceuticals for the etiological treatment of neurodegenerative protein-misfolding diseases (e. g., ALS, Alzheimer's or prion diseases) are available. In this brief communication the development of chaperone-based medications from medicinal plants (e. g., Ginkgo biloba) are reviewed as referred to specific protein-protein interactions of plant metallochaperones and human enzymes. It is indicated that bioactive copper chaperones for superoxide dismutase isolated from medicinal plants may be lead molecules for drug development in several diseases concerning metal ion metabolisms of man and animals.
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650 _ 7 |a J
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653 2 0 |2 Author
|a Metallophytochaperones
653 2 0 |2 Author
|a blood
653 2 0 |2 Author
|a Alzheimer's disease
653 2 0 |2 Author
|a plant extracts
653 2 0 |2 Author
|a CCS
653 2 0 |2 Author
|a Ginkgo biloba
653 2 0 |2 Author
|a SOD
653 2 0 |2 Author
|a apoenzymes
653 2 0 |2 Author
|a plant molecular farming
653 2 0 |2 Author
|a metal ion homeostasis
653 2 0 |2 Author
|a A beta
653 2 0 |2 Author
|a A beta PP
700 1 _ |a Garfin, D. E.
|b 1
|0 P:(DE-HGF)0
773 _ _ |a 10.2174/092986609787316234
|g Vol. 16, p. 116 - 120
|p 116 - 120
|q 16<116 - 120
|0 PERI:(DE-600)2136373-0
|t Protein and peptide letters
|v 16
|y 2009
|x 0929-8665
856 7 _ |u http://dx.doi.org/10.2174/092986609787316234
909 C O |o oai:juser.fz-juelich.de:552
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914 1 _ |y 2009
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |k ICG-3
|l Phytosphäre
|d 31.10.2010
|g ICG
|0 I:(DE-Juel1)ICG-3-20090406
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981 _ _ |a I:(DE-Juel1)IBG-2-20101118
981 _ _ |a I:(DE-Juel1)ICG-3-20090406


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