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@ARTICLE{Shah:56237,
      author       = {Shah, J. N. and Steinhoff, S. and Mirzazade, S. and
                      Zafiris, O. and Grosse-Ruyken, M. L. and Jäncke, R. K. and
                      Zilles, K.},
      title        = {{T}he effect of sequence repeat time on auditory cortex
                      stimulation during phonetic discrimination},
      journal      = {NeuroImage},
      volume       = {12},
      issn         = {1053-8119},
      address      = {Orlando, Fla.},
      publisher    = {Academic Press},
      reportid     = {PreJuSER-56237},
      pages        = {100 - 108},
      year         = {2000},
      note         = {Record converted from VDB: 12.11.2012},
      comment      = {NeuroImage Volume 12, Issue 1, July 2000, Pages 100-108},
      booktitle     = {NeuroImage Volume 12, Issue 1, July
                       2000, Pages 100-108},
      abstract     = {Acoustic noise generated by the MR scanner gradient system
                      during fMRI studies of auditory function is a very
                      significant potential confound. Despite these deleterious
                      effects, fMRI of the auditory cortex has been successful and
                      numerous practitioners have circumvented the problem of
                      acoustic masking noise. In the context of auditory cortex
                      fMRI, the sequence repeat time (TR) has the effect of
                      altering the length of time during which the scanner is
                      quiet. Indeed, the move to whole-brain fMRI makes the
                      problem of acoustic noise more acute and points to the need
                      to examine the role of TR and its influence on the BOLD
                      signal. The aim of this study was to examine the effect of
                      varying the TR time on activation of auditory cortex during
                      presentation and performance of a phonetic discrimination
                      task. The results presented here demonstrate that the
                      influence of sequence repeat time is considerable. For a
                      short repeat time it is likely that the noise from the
                      scanner is a significant mask and hinders accurate task
                      performance. At the other extreme, a repeat time of 9 s is
                      also suboptimal, probably due to attentional effects and
                      lack of concentration and not least because of the longer
                      overall measurement times. The results of this study point
                      to a complicated interplay between psychophysical factors as
                      well as physical parameters; attention, acoustic noise,
                      total duration of the experiment, consideration of the
                      volume of acquisition, and overall difficulty of the task
                      have to be assessed and balanced. For the paradigm used
                      here, the results suggest an optimal TR of around 6 s for a
                      16-slice acquisition.},
      keywords     = {Artifacts / Auditory Cortex: physiology / Discrimination
                      (Psychology): physiology / Humans / Magnetic Resonance
                      Imaging: instrumentation / Male / Noise / Perceptual Masking
                      / Phonetics / Time Factors / J (WoSType)},
      cin          = {IME},
      ddc          = {610},
      cid          = {I:(DE-Juel1)VDB54},
      pnm          = {Zerebrale Repräsentation},
      pid          = {G:(DE-Juel1)FUEK90},
      shelfmark    = {Neurosciences / Neuroimaging / Radiology, Nuclear Medicine
                      $\&$ Medical Imaging},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:10875906},
      UT           = {WOS:000088317700010},
      doi          = {10.1006/nimg.2000.0588},
      url          = {https://juser.fz-juelich.de/record/56237},
}