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@ARTICLE{Meszaros:56500,
      author       = {Meszaros, G. and Kronholz, S. and Karthäuser, S. and
                      Mayer, D. and Wandlowski, Th.},
      title        = {{E}lectrochemical {F}abrication and {C}haracterization of
                      {N}anocontacts and nm-sized {G}aps},
      journal      = {Applied physics / A},
      volume       = {87},
      issn         = {0947-8396},
      address      = {Berlin},
      publisher    = {Springer},
      reportid     = {PreJuSER-56500},
      pages        = {569 - 575},
      year         = {2007},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Comparison of pulmonary outcomes after off-pump coronary
                      artery bypass (OPCAB) vs on-pump coronary artery grafting
                      with cardiopulmonary bypass (CABG/CPB). Study design: We
                      examined preoperative and postoperative respiratory
                      compliance, fluid balance, hemodynamics, arterial blood
                      gases, chest radiographs, spirometry, pulmonary
                      complications, and time to extubation in a prospective trial
                      of 200 patients randomized to OPCAB vs CABG/CPB performed by
                      one surgeon.One CABG/CPB patient and two OPCAB patients
                      required mitral valve repair or replacement and were
                      withdrawn. After three crossovers from CABG/CBP to OPCAB and
                      one crossover from OPCAB to CABG, 97 CABG/CPB patients and
                      100 OPCAB patients remained. There were no significant
                      preoperative demographic differences between groups.
                      Postoperative compliance was reduced more after OPCAB than
                      after CABG/CPB (- 15.4 +/- 10.7 mL/cm H(2)O vs - 11.2 +/-
                      10.1 mL/cm H(2)O [mean +/- SD]; p = 0.007), associated with
                      rotation of the heart into the right chest to perform
                      posterolateral bypasses (p < 0.001) and the concomitant
                      increased fluid requirements necessary to maintain
                      hemodynamic stability during rotation of the heart. In
                      addition to higher intraoperative fluid intake (4,541 +/-
                      1,311 mL vs 3,585 +/- 1,033 mL, p < 0.0001), OPCAB patients
                      had higher intraoperative fluid balance (3,903 +/- 1,315 mL
                      vs 1,772 +/- 1,373 mL, p < 0.0001), and higher postoperative
                      pulmonary arterial diastolic pressure (15.0 +/- 5.5 mm Hg vs
                      11.8 +/- 5.2 mm Hg, p < 0.0001) and central venous pressure
                      (10.4 +/- 4.5 mm Hg vs 8.4 +/- 4.7 mm Hg, p < 0.0001).
                      Despite lower compliance, immediate postoperative Pao(2) on
                      fraction of inspired oxygen of 1.0 (275 +/- 97 torr vs 221
                      +/- 92 torr, p = 0.001) was higher after OPCAB and
                      extubation was earlier (p = 0.001). Postoperative chest
                      radiographs, spirometry, mortality, reintubation, or
                      readmission for pulmonary complications were not different
                      between groups.Compared to CABG/CPB, OPCAB was associated
                      with a greater reduction in postoperative respiratory
                      compliance associated with increased fluid administration
                      and rotation of the heart into the right chest to perform
                      posterolateral grafts. OPCAB yielded better gas exchange and
                      earlier extubation but no difference in chest radiographs,
                      spirometry, or rates of death, pneumonia, pleural effusion,
                      or pulmonary edema.},
      keywords     = {Cardiopulmonary Bypass / Coronary Artery Bypass: adverse
                      effects / Coronary Artery Bypass, Off-Pump: adverse effects
                      / Female / Humans / Lung Compliance / Lung Diseases:
                      etiology / Male / Middle Aged / Pulmonary Gas Exchange /
                      Radiography, Thoracic / Spirometry / Treatment Outcome /
                      Water-Electrolyte Balance / J (WoSType)},
      cin          = {CNI / IBN-2 / IBN-3 / IFF-6 / JARA-FIT},
      ddc          = {530},
      cid          = {I:(DE-Juel1)VDB381 / I:(DE-Juel1)IBN-2-20090406 /
                      I:(DE-Juel1)VDB801 / I:(DE-Juel1)VDB786 /
                      $I:(DE-82)080009_20140620$},
      pnm          = {Grundlagen für zukünftige Informationstechnologien},
      pid          = {G:(DE-Juel1)FUEK412},
      shelfmark    = {Materials Science, Multidisciplinary / Physics, Applied},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:15764773},
      UT           = {WOS:000244950900034},
      doi          = {10.1007/s00339-007-3903-2},
      url          = {https://juser.fz-juelich.de/record/56500},
}