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005     20180211181124.0
024 7 _ |2 pmid
|a pmid:15764773
024 7 _ |2 DOI
|a 10.1007/s00339-007-3903-2
024 7 _ |2 WOS
|a WOS:000244950900034
024 7 _ |2 ISSN
|a 0947-8396
037 _ _ |a PreJuSER-56500
041 _ _ |a eng
082 _ _ |a 530
084 _ _ |2 WoS
|a Materials Science, Multidisciplinary
084 _ _ |2 WoS
|a Physics, Applied
100 1 _ |a Meszaros, G.
|b 0
|u FZJ
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245 _ _ |a Electrochemical Fabrication and Characterization of Nanocontacts and nm-sized Gaps
260 _ _ |c 2007
|a Berlin
|b Springer
300 _ _ |a 569 - 575
336 7 _ |a Journal Article
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336 7 _ |a article
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440 _ 0 |a Applied Physics A
|x 0947-8396
|0 560
|v 87
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a Comparison of pulmonary outcomes after off-pump coronary artery bypass (OPCAB) vs on-pump coronary artery grafting with cardiopulmonary bypass (CABG/CPB). Study design: We examined preoperative and postoperative respiratory compliance, fluid balance, hemodynamics, arterial blood gases, chest radiographs, spirometry, pulmonary complications, and time to extubation in a prospective trial of 200 patients randomized to OPCAB vs CABG/CPB performed by one surgeon.One CABG/CPB patient and two OPCAB patients required mitral valve repair or replacement and were withdrawn. After three crossovers from CABG/CBP to OPCAB and one crossover from OPCAB to CABG, 97 CABG/CPB patients and 100 OPCAB patients remained. There were no significant preoperative demographic differences between groups. Postoperative compliance was reduced more after OPCAB than after CABG/CPB (- 15.4 +/- 10.7 mL/cm H(2)O vs - 11.2 +/- 10.1 mL/cm H(2)O [mean +/- SD]; p = 0.007), associated with rotation of the heart into the right chest to perform posterolateral bypasses (p < 0.001) and the concomitant increased fluid requirements necessary to maintain hemodynamic stability during rotation of the heart. In addition to higher intraoperative fluid intake (4,541 +/- 1,311 mL vs 3,585 +/- 1,033 mL, p < 0.0001), OPCAB patients had higher intraoperative fluid balance (3,903 +/- 1,315 mL vs 1,772 +/- 1,373 mL, p < 0.0001), and higher postoperative pulmonary arterial diastolic pressure (15.0 +/- 5.5 mm Hg vs 11.8 +/- 5.2 mm Hg, p < 0.0001) and central venous pressure (10.4 +/- 4.5 mm Hg vs 8.4 +/- 4.7 mm Hg, p < 0.0001). Despite lower compliance, immediate postoperative Pao(2) on fraction of inspired oxygen of 1.0 (275 +/- 97 torr vs 221 +/- 92 torr, p = 0.001) was higher after OPCAB and extubation was earlier (p = 0.001). Postoperative chest radiographs, spirometry, mortality, reintubation, or readmission for pulmonary complications were not different between groups.Compared to CABG/CPB, OPCAB was associated with a greater reduction in postoperative respiratory compliance associated with increased fluid administration and rotation of the heart into the right chest to perform posterolateral grafts. OPCAB yielded better gas exchange and earlier extubation but no difference in chest radiographs, spirometry, or rates of death, pneumonia, pleural effusion, or pulmonary edema.
536 _ _ |a Grundlagen für zukünftige Informationstechnologien
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650 _ 2 |2 MeSH
|a Cardiopulmonary Bypass
650 _ 2 |2 MeSH
|a Coronary Artery Bypass: adverse effects
650 _ 2 |2 MeSH
|a Coronary Artery Bypass, Off-Pump: adverse effects
650 _ 2 |2 MeSH
|a Female
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Lung Compliance
650 _ 2 |2 MeSH
|a Lung Diseases: etiology
650 _ 2 |2 MeSH
|a Male
650 _ 2 |2 MeSH
|a Middle Aged
650 _ 2 |2 MeSH
|a Pulmonary Gas Exchange
650 _ 2 |2 MeSH
|a Radiography, Thoracic
650 _ 2 |2 MeSH
|a Spirometry
650 _ 2 |2 MeSH
|a Treatment Outcome
650 _ 2 |2 MeSH
|a Water-Electrolyte Balance
650 _ 7 |a J
|2 WoSType
700 1 _ |a Kronholz, S.
|b 1
|u FZJ
|0 P:(DE-Juel1)VDB34541
700 1 _ |a Karthäuser, S.
|b 2
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|0 P:(DE-Juel1)130751
700 1 _ |a Mayer, D.
|b 3
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|0 P:(DE-Juel1)128707
700 1 _ |a Wandlowski, Th.
|b 4
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|0 P:(DE-Juel1)VDB9859
773 _ _ |0 PERI:(DE-600)1398311-8
|a 10.1007/s00339-007-3903-2
|g Vol. 87, p. 569 - 575
|p 569 - 575
|q 87<569 - 575
|t Applied physics / A
|v 87
|x 0947-8396
|y 2007
856 7 _ |u http://dx.doi.org/10.1007/s00339-007-3903-2
909 C O |o oai:juser.fz-juelich.de:56500
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