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@ARTICLE{Krause:57200,
author = {Krause, H.-J. and Wolters, N. and Zhang, Y. and
Offenhäusser, A. and Miethe, P. and Meyer, M. H. F. and
Hartmann, M. and Keusgen, M.},
title = {{M}agnetic particle detection by frequency mixing for
immunoassay applications},
journal = {Journal of magnetism and magnetic materials},
volume = {311},
issn = {0304-8853},
address = {Amsterdam},
publisher = {North-Holland Publ. Co.},
reportid = {PreJuSER-57200},
pages = {436 - 444},
year = {2007},
note = {Record converted from VDB: 12.11.2012},
abstract = {For magnetic immunoassay applications, a novel magnetic
reader for quantification of magnetic particle
concentrations has been developed. Upon magnetic excitation
at two distinct frequencies incident on the sample, the
response signal generated at a sum frequency is detected.
The low-frequency field component periodically drives the
magnetic particles into saturation, which is probed by the
high-frequency field. The appearance of frequency mixing
lines is highly specific to the nonlinearity of the
superparamagnetic particles' magnetization. The optimization
of field coils, differential pickup coil, preamplifier,
demodulators and filters are discussed. The output signal is
linear for four orders of magnitude in iron concentration.
(C) 2006 Elsevier B.V. All rights reserved.},
keywords = {J (WoSType)},
cin = {CNI / IBN-2 / JARA-FIT},
ddc = {530},
cid = {I:(DE-Juel1)VDB381 / I:(DE-Juel1)IBN-2-20090406 /
$I:(DE-82)080009_20140620$},
pnm = {Grundlagen für zukünftige Informationstechnologien},
pid = {G:(DE-Juel1)FUEK412},
shelfmark = {Materials Science, Multidisciplinary / Physics, Condensed
Matter},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000245524800088},
doi = {10.1016/j.jmmm.2006.10.1164},
url = {https://juser.fz-juelich.de/record/57200},
}