Hauptseite > Publikationsdatenbank > Magnetic particle detection by frequency mixing for immunoassay applications > print

001     57200
005     20190625111541.0
024 7 _ |2 DOI
|a 10.1016/j.jmmm.2006.10.1164
024 7 _ |2 WOS
|a WOS:000245524800088
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037 _ _ |a PreJuSER-57200
041 _ _ |a eng
082 _ _ |a 530
084 _ _ |2 WoS
|a Materials Science, Multidisciplinary
084 _ _ |2 WoS
|a Physics, Condensed Matter
100 1 _ |a Krause, H.-J.
|b 0
|u FZJ
|0 P:(DE-Juel1)128697
245 _ _ |a Magnetic particle detection by frequency mixing for immunoassay applications
260 _ _ |a Amsterdam
|b North-Holland Publ. Co.
|c 2007
300 _ _ |a 436 - 444
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
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336 7 _ |a Journal Article
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|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |a Journal of Magnetism and Magnetic Materials
|x 0304-8853
|0 3490
|v 311
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a For magnetic immunoassay applications, a novel magnetic reader for quantification of magnetic particle concentrations has been developed. Upon magnetic excitation at two distinct frequencies incident on the sample, the response signal generated at a sum frequency is detected. The low-frequency field component periodically drives the magnetic particles into saturation, which is probed by the high-frequency field. The appearance of frequency mixing lines is highly specific to the nonlinearity of the superparamagnetic particles' magnetization. The optimization of field coils, differential pickup coil, preamplifier, demodulators and filters are discussed. The output signal is linear for four orders of magnitude in iron concentration. (C) 2006 Elsevier B.V. All rights reserved.
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650 _ 7 |a J
|2 WoSType
653 2 0 |2 Author
|a magnetic detection
653 2 0 |2 Author
|a frequency mixing
653 2 0 |2 Author
|a superparamagnetism
653 2 0 |2 Author
|a nonlinearity
653 2 0 |2 Author
|a induction coil
653 2 0 |2 Author
|a immunoassay
700 1 _ |a Wolters, N.
|b 1
|u FZJ
|0 P:(DE-Juel1)VDB5403
700 1 _ |a Zhang, Y.
|b 2
|u FZJ
|0 P:(DE-Juel1)VDB5476
700 1 _ |a Offenhäusser, A.
|b 3
|u FZJ
|0 P:(DE-Juel1)128713
700 1 _ |a Miethe, P.
|b 4
|0 P:(DE-HGF)0
700 1 _ |a Meyer, M. H. F.
|b 5
|0 P:(DE-HGF)0
700 1 _ |a Hartmann, M.
|b 6
|0 P:(DE-HGF)0
700 1 _ |a Keusgen, M.
|b 7
|0 P:(DE-HGF)0
773 _ _ |a 10.1016/j.jmmm.2006.10.1164
|g Vol. 311, p. 436 - 444
|p 436 - 444
|q 311<436 - 444
|0 PERI:(DE-600)1479000-2
|t Journal of magnetism and magnetic materials
|v 311
|y 2007
|x 0304-8853
856 7 _ |u http://dx.doi.org/10.1016/j.jmmm.2006.10.1164
909 C O |o oai:juser.fz-juelich.de:57200
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913 1 _ |k P42
|v Grundlagen für zukünftige Informationstechnologien
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914 1 _ |y 2007
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |d 14.09.2008
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920 1 _ |d 31.12.2010
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|l Bioelektronik
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920 1 _ |0 I:(DE-82)080009_20140620
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|l Jülich-Aachen Research Alliance - Fundamentals of Future Information Technology
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