001     57204
005     20161225184246.0
024 7 _ |2 pmid
|a pmid:17011649
024 7 _ |2 DOI
|a 10.1016/j.mimet.2006.08.004
024 7 _ |2 WOS
|a WOS:000244382400003
037 _ _ |a PreJuSER-57204
041 _ _ |a eng
082 _ _ |a 570
084 _ _ |2 WoS
|a Biochemical Research Methods
084 _ _ |2 WoS
|a Microbiology
100 1 _ |a Meyer, M. H. F.
|b 0
|0 P:(DE-HGF)0
245 _ _ |a Magnetic biosensor for the detection of Yersinia pestis
260 _ _ |a New York, NY
|b Elsevier
|c 2007
300 _ _ |a 218 - 224
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
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336 7 _ |a Journal Article
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|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |a Journal of Microbiological Methods
|x 0167-7012
|0 3539
|v 68
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a A novel type of magnetic-beads based magnetic biosensor is described for the detection of Yersinia pestis. Experiments were performed with the antigen fraction F1 of these bacteria. The magnetic sensor platform offers easy and reliable detection of Y. pestis by the use of magnetic beads for labelling and quantification in a single step due to their paramagnetic features. The system uses antiYPF1 antibodies as capture element on ABICAP columns as core element of the magnetic sensor. Several immobilization methods for antibodies on polyethylene were exploited. The established biosensor has a linear detection range of 25-300 ng/ml Y. pestis antigen F1 and a detection limit of 2.5 ng/ml in buffer and human blood serum. The presented sensor system is small, simple, portable and therefore usable as off-lab detection unit for medical and warfare analytes.
536 _ _ |a Grundlagen für zukünftige Informationstechnologien
|c P42
|2 G:(DE-HGF)
|0 G:(DE-Juel1)FUEK412
|x 0
588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Animals
650 _ 2 |2 MeSH
|a Antibodies, Bacterial: chemistry
650 _ 2 |2 MeSH
|a Antigens, Bacterial: blood
650 _ 2 |2 MeSH
|a Biosensing Techniques: instrumentation
650 _ 2 |2 MeSH
|a Biosensing Techniques: methods
650 _ 2 |2 MeSH
|a Cell Line
650 _ 2 |2 MeSH
|a Immunomagnetic Separation: instrumentation
650 _ 2 |2 MeSH
|a Immunomagnetic Separation: methods
650 _ 2 |2 MeSH
|a Mice
650 _ 2 |2 MeSH
|a Plague: microbiology
650 _ 2 |2 MeSH
|a Yersinia pestis: isolation & purification
650 _ 7 |0 0
|2 NLM Chemicals
|a Antibodies, Bacterial
650 _ 7 |0 0
|2 NLM Chemicals
|a Antigens, Bacterial
650 _ 7 |a J
|2 WoSType
653 2 0 |2 Author
|a Yersinia pestis
653 2 0 |2 Author
|a antiYPF1
653 2 0 |2 Author
|a magnetic detection
653 2 0 |2 Author
|a magnetic beads
700 1 _ |a Stehr, M.
|b 1
|0 P:(DE-HGF)0
700 1 _ |a Bhuju, S.
|b 2
|0 P:(DE-HGF)0
700 1 _ |a Krause, H.-J.
|b 3
|u FZJ
|0 P:(DE-Juel1)128697
700 1 _ |a Hartmann, M.
|b 4
|0 P:(DE-HGF)0
700 1 _ |a Miethe, P.
|b 5
|0 P:(DE-HGF)0
700 1 _ |a Singh, M.
|b 6
|0 P:(DE-HGF)0
700 1 _ |a Keusgen, M.
|b 7
|0 P:(DE-HGF)0
773 _ _ |a 10.1016/j.mimet.2006.08.004
|g Vol. 68, p. 218 - 224
|p 218 - 224
|q 68<218 - 224
|0 PERI:(DE-600)1483012-7
|t Journal of microbiological methods
|v 68
|y 2007
|x 0167-7012
856 7 _ |u http://dx.doi.org/10.1016/j.mimet.2006.08.004
909 C O |o oai:juser.fz-juelich.de:57204
|p VDB
913 1 _ |k P42
|v Grundlagen für zukünftige Informationstechnologien
|l Grundlagen für zukünftige Informationstechnologien (FIT)
|b Schlüsseltechnologien
|0 G:(DE-Juel1)FUEK412
|x 0
914 1 _ |y 2007
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |k CNI
|l Center of Nanoelectronic Systems for Information Technology
|d 14.09.2008
|g CNI
|z 381
|0 I:(DE-Juel1)VDB381
|x 1
920 1 _ |k IBN-2
|l Bioelektronik
|d 31.12.2010
|g IBN
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|x 0
970 _ _ |a VDB:(DE-Juel1)89981
980 _ _ |a VDB
980 _ _ |a ConvertedRecord
980 _ _ |a journal
980 _ _ |a I:(DE-Juel1)VDB381
980 _ _ |a I:(DE-Juel1)IBN-2-20090406
980 _ _ |a UNRESTRICTED
981 _ _ |a I:(DE-Juel1)IBN-2-20090406


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