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024 7 _ |2 DOI
|a 10.1016/j.cplett.2005.11.019
024 7 _ |2 WOS
|a WOS:000235104200010
037 _ _ |a PreJuSER-57916
041 _ _ |a eng
082 _ _ |a 540
084 _ _ |2 WoS
|a Chemistry, Physical
084 _ _ |2 WoS
|a Physics, Atomic, Molecular & Chemical
100 1 _ |a Ortore, M. G.
|b 0
|0 P:(DE-HGF)0
245 _ _ |a High pressure small-angle scattering study of the aggregation state of beta-lactoglobulin in water and in water/ethylene-glycol solutions
260 _ _ |a Amsterdam [u.a.]
|b Elsevier
|c 2006
300 _ _ |a
336 7 _ |a Journal Article
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336 7 _ |a JOURNAL_ARTICLE
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336 7 _ |a article
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440 _ 0 |a Chemical Physics Letters
|x 0009-2614
|0 1200
|y 4
|v 418
500 _ _ |a Record converted from VDB: 12.11.2012
520 _ _ |a High-pressure SANS experiments have been performed on acidic dilute solutions of the dimeric protein P-lactoglobulin. To evidence the solvent effect on the protein stability during compression, two different solvents, D2O and a 50% w/w mixture of water and ethyleneglycol have been considered. Data confirm that pressure induces dissociation in both solvents, even if P-lactoglobulin shows an higher stability in 50% ethylene-glycol. An original global fitting procedure has been used to derive the thermodynamic parameters that describe the dissociation equilibrium. As a result, the role of the solvent in protein dissociation has been observed to reflect on volume and compressibility changes. (c) 2005 Elsevier B.V. All rights reserved.
536 _ _ |a Kondensierte Materie
|c P54
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536 _ _ |a Großgeräte für die Forschung mit Photonen, Neutronen und Ionen (PNI)
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588 _ _ |a Dataset connected to Web of Science
650 _ 7 |a J
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700 1 _ |a Spinozzi, F.
|b 1
|0 P:(DE-HGF)0
700 1 _ |a Carsughi, F.
|b 2
|u FZJ
|0 P:(DE-Juel1)VDB2958
700 1 _ |a Mariani, P.
|b 3
|0 P:(DE-HGF)0
700 1 _ |a Bonetti, M.
|b 4
|0 P:(DE-HGF)0
700 1 _ |a Onori, G.
|b 5
|0 P:(DE-HGF)0
773 _ _ |a 10.1016/j.cplett.2005.11.019
|g Vol. 418
|q 418
|0 PERI:(DE-600)1466293-0
|t Chemical physics letters
|v 418
|y 2006
|x 0009-2614
856 7 _ |u http://dx.doi.org/10.1016/j.cplett.2005.11.019
909 C O |o oai:juser.fz-juelich.de:57916
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|b Struktur der Materie
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914 1 _ |a Nachtrag
|y 2006
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
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|d 31.12.2006
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981 _ _ |a I:(DE-Juel1)JCNS-1-20110106
981 _ _ |a I:(DE-Juel1)ICS-1-20110106


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