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000058391 0247_ $$2DOI$$a10.1016/j.ejrad.2007.09.015
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000058391 084__ $$2WoS$$aRadiology, Nuclear Medicine & Medical Imaging
000058391 1001_ $$0P:(DE-HGF)0$$aMamisch, T.Ch.$$b0
000058391 245__ $$aSteady-state diffusion imaging for MR in-vivo evaluation of reparative cartilage after matrix-associated autologous chondrocyte transplantation at 3 Tesla - preliminary results
000058391 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2008
000058391 300__ $$a72 - 79
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000058391 440_0 $$018544$$aEuropean Journal of Radiology$$v65$$x0720-048x
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000058391 520__ $$aTo demonstrate the feasibility of time-reversed fast imaging with steady-state precession (FISP) called PSIF for diffusion-weighted imaging of cartilage and cartilage transplants in a clinical study.In a cross-sectional study 15 patients underwent MRI using a 3D partially balanced steady-state gradient echo pulse sequence with and without diffusion weighting at two different time points after matrix-associated autologous cartilage transplantation (MACT). Mean diffusion quotients (signal intensity without diffusion-weighting divided by signal intensity with diffusion weighting) within the cartilage transplants were compared to diffusion quotients found in normal cartilage.The global diffusion quotient found in repair cartilage was significantly higher than diffusion values in normal cartilage (p<0.05). There was a decrease between the earlier and the later time point after surgery.In-vivo diffusion-weighted imaging based on the PSIF technique is possible. Our preliminary results show follow-up of cartilage transplant maturation in patients may provide additional information to morphological assessment.
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000058391 650_2 $$2MeSH$$aAdult
000058391 650_2 $$2MeSH$$aAnalysis of Variance
000058391 650_2 $$2MeSH$$aCartilage, Articular: metabolism
000058391 650_2 $$2MeSH$$aCartilage, Articular: pathology
000058391 650_2 $$2MeSH$$aCell Transplantation: methods
000058391 650_2 $$2MeSH$$aChondrocytes: transplantation
000058391 650_2 $$2MeSH$$aCross-Sectional Studies
000058391 650_2 $$2MeSH$$aDiffusion Magnetic Resonance Imaging: methods
000058391 650_2 $$2MeSH$$aFemale
000058391 650_2 $$2MeSH$$aFollow-Up Studies
000058391 650_2 $$2MeSH$$aHumans
000058391 650_2 $$2MeSH$$aImaging, Three-Dimensional
000058391 650_2 $$2MeSH$$aKnee Joint: surgery
000058391 650_2 $$2MeSH$$aMale
000058391 650_2 $$2MeSH$$aTreatment Outcome
000058391 650_7 $$2WoSType$$aJ
000058391 65320 $$2Author$$amagnetic resonance imaging
000058391 65320 $$2Author$$aarticular cartilage
000058391 65320 $$2Author$$adiffusion weighted imaging
000058391 65320 $$2Author$$a3T
000058391 65320 $$2Author$$amatrix-associated autologous chondrocyte transplantation
000058391 7001_ $$0P:(DE-Juel1)VDB63505$$aMenzel, M. I.$$b1$$uFZJ
000058391 7001_ $$0P:(DE-HGF)0$$aWelsch, G. H.$$b2
000058391 7001_ $$0P:(DE-HGF)0$$aBittersohl, B.$$b3
000058391 7001_ $$0P:(DE-HGF)0$$aSalomonowitz, E.$$b4
000058391 7001_ $$0P:(DE-HGF)0$$aSzomolanyi, P.$$b5
000058391 7001_ $$0P:(DE-HGF)0$$aKordelle, J.$$b6
000058391 7001_ $$0P:(DE-HGF)0$$aMarlovits, St.$$b7
000058391 7001_ $$0P:(DE-HGF)0$$aTrattnig, S.$$b8
000058391 773__ $$0PERI:(DE-600)2005350-2$$a10.1016/j.ejrad.2007.09.015$$gVol. 65, p. 72 - 79$$p72 - 79$$q65<72 - 79$$tEuropean journal of radiology$$v65$$x0720-048x$$y2008
000058391 8567_ $$uhttp://dx.doi.org/10.1016/j.ejrad.2007.09.015
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