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@ARTICLE{Mamisch:58391,
author = {Mamisch, T.Ch. and Menzel, M. I. and Welsch, G. H. and
Bittersohl, B. and Salomonowitz, E. and Szomolanyi, P. and
Kordelle, J. and Marlovits, St. and Trattnig, S.},
title = {{S}teady-state diffusion imaging for {MR} in-vivo
evaluation of reparative cartilage after matrix-associated
autologous chondrocyte transplantation at 3 {T}esla -
preliminary results},
journal = {European journal of radiology},
volume = {65},
issn = {0720-048x},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {PreJuSER-58391},
pages = {72 - 79},
year = {2008},
note = {Record converted from VDB: 12.11.2012},
abstract = {To demonstrate the feasibility of time-reversed fast
imaging with steady-state precession (FISP) called PSIF for
diffusion-weighted imaging of cartilage and cartilage
transplants in a clinical study.In a cross-sectional study
15 patients underwent MRI using a 3D partially balanced
steady-state gradient echo pulse sequence with and without
diffusion weighting at two different time points after
matrix-associated autologous cartilage transplantation
(MACT). Mean diffusion quotients (signal intensity without
diffusion-weighting divided by signal intensity with
diffusion weighting) within the cartilage transplants were
compared to diffusion quotients found in normal
cartilage.The global diffusion quotient found in repair
cartilage was significantly higher than diffusion values in
normal cartilage (p<0.05). There was a decrease between the
earlier and the later time point after surgery.In-vivo
diffusion-weighted imaging based on the PSIF technique is
possible. Our preliminary results show follow-up of
cartilage transplant maturation in patients may provide
additional information to morphological assessment.},
keywords = {Adult / Analysis of Variance / Cartilage, Articular:
metabolism / Cartilage, Articular: pathology / Cell
Transplantation: methods / Chondrocytes: transplantation /
Cross-Sectional Studies / Diffusion Magnetic Resonance
Imaging: methods / Female / Follow-Up Studies / Humans /
Imaging, Three-Dimensional / Knee Joint: surgery / Male /
Treatment Outcome / J (WoSType)},
cin = {ICG-3},
ddc = {610},
cid = {I:(DE-Juel1)ICG-3-20090406},
pnm = {Terrestrische Umwelt},
pid = {G:(DE-Juel1)FUEK407},
shelfmark = {Radiology, Nuclear Medicine $\&$ Medical Imaging},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:17977685},
UT = {WOS:000253086400009},
doi = {10.1016/j.ejrad.2007.09.015},
url = {https://juser.fz-juelich.de/record/58391},
}