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000058660 084__ $$2WoS$$aMaterials Science, Multidisciplinary
000058660 084__ $$2WoS$$aPhysics, Applied
000058660 1001_ $$0P:(DE-Juel1)VDB57079$$aKomsiyska, L.$$b0$$uFZJ
000058660 245__ $$aElectrochemical Formation and Properties of Thin Polyaniline Films on Au(111) and p-Si(111)
000058660 260__ $$aBerlin$$bSpringer$$c2007
000058660 300__ $$a405 - 409
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000058660 440_0 $$0560$$aApplied Physics A$$v87$$x0947-8396
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000058660 520__ $$aIn hypertensive subjects, it has been demonstrated that the lower the blood pressure, the lower the incidence of chronic kidney disease (CKD). However, whether this relationship holds true in individuals without hypertension--that is, in individuals with a blood pressure <140/90 mmHg--remains unknown. This study was performed to assess the relationship between blood pressure and CKD in a Japanese population without hypertension. Among 13,007 Japanese participants in a general health screening, 9,596 (5,691 men and 3,905 women) were found to have either normal blood pressure or prehypertension, and were enrolled in this study. We categorized these individuals' blood pressure into six classes: BP-C1, <90/<65 mmHg; BP-C2, 90-100/65-70 mmHg; BP-C3, 100-110/70-75 mmHg; BP-C4, 110-120/75-80 mmHg; BP-C5, 120-130/80-85 mmHg; and BP-C6, 130-140/85-90 mmHg. Albuminuria was defined as a urinary albumin excretion ratio of > or =30 mg/g. Low estimated glomerular filtration rate (eGFR) was defined as eGFR <60 mL/min/1.73 m2. In men, when BP-C3 was used as a reference, multivariate logistic regression analysis adjusted for age, body mass index, serum lipid profiles, fasting plasma glucose and smoking status showed that BP-C1, BP-C2, BP-C4, BP-C5 and BP-C6 were associated with albuminuria with an adjusted odds ratio of 1.85 (0.53-6.46), 1.22 (0.59-2.51), 1.62 (1.01-2.59), 2.57 (1.64-4.02), and 3.81 (2.44-5.96). In women, the adjusted odds ratios of the risk for albuminuria in BP-C2, BP-C3, BP-C4, BP-C5 and BP-C6, as compared with BP-C1 as a reference, were 1.83 (0.70-4.79), 2.13 (0.84-5.42), 2.80 (1.10-7.14), 2.59 (0.99-6.78), and 3.99 (1.50-10.64). Blood pressure was not significantly associated with low eGFR in either gender. The risk for albuminuria was significantly greater when blood pressure exceeded 110/75 mmHg in both genders.
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000058660 650_2 $$2MeSH$$aAdult
000058660 650_2 $$2MeSH$$aAged
000058660 650_2 $$2MeSH$$aAlbuminuria: epidemiology
000058660 650_2 $$2MeSH$$aAlbuminuria: physiopathology
000058660 650_2 $$2MeSH$$aBlood Pressure
000058660 650_2 $$2MeSH$$aChronic Disease
000058660 650_2 $$2MeSH$$aFemale
000058660 650_2 $$2MeSH$$aGlomerular Filtration Rate
000058660 650_2 $$2MeSH$$aHumans
000058660 650_2 $$2MeSH$$aHypertension: complications
000058660 650_2 $$2MeSH$$aKidney Diseases: etiology
000058660 650_2 $$2MeSH$$aKidney Diseases: physiopathology
000058660 650_2 $$2MeSH$$aMale
000058660 650_2 $$2MeSH$$aMiddle Aged
000058660 650_2 $$2MeSH$$aPrevalence
000058660 650_7 $$2WoSType$$aJ
000058660 7001_ $$0P:(DE-Juel1)VDB58796$$aTsakova, V.$$b1$$uFZJ
000058660 7001_ $$0P:(DE-Juel1)VDB13645$$aStaikov, G.$$b2$$uFZJ
000058660 773__ $$0PERI:(DE-600)1398311-8$$a10.1007/s00339-007-3905-0$$gVol. 87, p. 405 - 409$$p405 - 409$$q87<405 - 409$$tApplied physics / A$$v87$$x0947-8396$$y2007
000058660 8567_ $$uhttp://dx.doi.org/10.1007/s00339-007-3905-0
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